Matches in SemOpenAlex for { <https://semopenalex.org/work/W4239333556> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W4239333556 abstract "Selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), and atypical antidepressants are considered first-line agents for depression in the intensive care unit (ICU) setting, and are preferred over older antidepressants due to their more benign side effect profile and tolerability. This chapter reviews the literature on the use of antidepressants in the ICU. Common side effects of SSRIs include insomnia and gastrointestinal discomfort, while citalopram may uniquely cause prolongation of the QTc interval. All SSRIs carry a risk for the development of serotonin syndrome following overdose. SNRIs are similar to SSRIs in their side effect profile, although they are more likely to cause hypertension. Mirtazapine is strongly associated with sedation and weight gain. Stimulants may also be used to treat depression in the medically ill, and can be particularly effective in treating apathy, low energy, and loss of appetite. Monotherapy is typically the initial treatment strategy and low doses are generally recommended in the ICU setting. Efficacy may not be apparent for up to 8 weeks. Patients who have been taking an antidepressant prior to their arrival in the ICU should continue on the medication so as to prevent discontinuation syndrome. Delirium may warrant cessation of the antidepressant and potentially dangerous medication interactions also need to be evaluated. At present, there is no evidence to suggest that an antidepressant should be initiated after a significant physical or emotional trauma." @default.
- W4239333556 created "2022-05-12" @default.
- W4239333556 creator A5042464218 @default.
- W4239333556 creator A5067682955 @default.
- W4239333556 date "2016-04-01" @default.
- W4239333556 modified "2023-09-27" @default.
- W4239333556 title "Antidepressants in critical illness" @default.
- W4239333556 doi "https://doi.org/10.1093/med/9780199600830.003.0044" @default.
- W4239333556 hasPublicationYear "2016" @default.
- W4239333556 type Work @default.
- W4239333556 citedByCount "0" @default.
- W4239333556 crossrefType "book" @default.
- W4239333556 hasAuthorship W4239333556A5042464218 @default.
- W4239333556 hasAuthorship W4239333556A5067682955 @default.
- W4239333556 hasConcept C118552586 @default.
- W4239333556 hasConcept C126322002 @default.
- W4239333556 hasConcept C170493617 @default.
- W4239333556 hasConcept C177713679 @default.
- W4239333556 hasConcept C197934379 @default.
- W4239333556 hasConcept C2775864247 @default.
- W4239333556 hasConcept C2776134451 @default.
- W4239333556 hasConcept C2776376669 @default.
- W4239333556 hasConcept C2776466888 @default.
- W4239333556 hasConcept C2777490545 @default.
- W4239333556 hasConcept C2778375690 @default.
- W4239333556 hasConcept C2778715236 @default.
- W4239333556 hasConcept C2779177272 @default.
- W4239333556 hasConcept C2779753318 @default.
- W4239333556 hasConcept C2780179036 @default.
- W4239333556 hasConcept C2781068410 @default.
- W4239333556 hasConcept C31487548 @default.
- W4239333556 hasConcept C37000724 @default.
- W4239333556 hasConcept C42219234 @default.
- W4239333556 hasConcept C558461103 @default.
- W4239333556 hasConcept C71924100 @default.
- W4239333556 hasConceptScore W4239333556C118552586 @default.
- W4239333556 hasConceptScore W4239333556C126322002 @default.
- W4239333556 hasConceptScore W4239333556C170493617 @default.
- W4239333556 hasConceptScore W4239333556C177713679 @default.
- W4239333556 hasConceptScore W4239333556C197934379 @default.
- W4239333556 hasConceptScore W4239333556C2775864247 @default.
- W4239333556 hasConceptScore W4239333556C2776134451 @default.
- W4239333556 hasConceptScore W4239333556C2776376669 @default.
- W4239333556 hasConceptScore W4239333556C2776466888 @default.
- W4239333556 hasConceptScore W4239333556C2777490545 @default.
- W4239333556 hasConceptScore W4239333556C2778375690 @default.
- W4239333556 hasConceptScore W4239333556C2778715236 @default.
- W4239333556 hasConceptScore W4239333556C2779177272 @default.
- W4239333556 hasConceptScore W4239333556C2779753318 @default.
- W4239333556 hasConceptScore W4239333556C2780179036 @default.
- W4239333556 hasConceptScore W4239333556C2781068410 @default.
- W4239333556 hasConceptScore W4239333556C31487548 @default.
- W4239333556 hasConceptScore W4239333556C37000724 @default.
- W4239333556 hasConceptScore W4239333556C42219234 @default.
- W4239333556 hasConceptScore W4239333556C558461103 @default.
- W4239333556 hasConceptScore W4239333556C71924100 @default.
- W4239333556 hasLocation W42393335561 @default.
- W4239333556 hasOpenAccess W4239333556 @default.
- W4239333556 hasPrimaryLocation W42393335561 @default.
- W4239333556 hasRelatedWork W13671264 @default.
- W4239333556 hasRelatedWork W14465827 @default.
- W4239333556 hasRelatedWork W148072 @default.
- W4239333556 hasRelatedWork W1645763 @default.
- W4239333556 hasRelatedWork W16905729 @default.
- W4239333556 hasRelatedWork W3313712 @default.
- W4239333556 hasRelatedWork W3395975 @default.
- W4239333556 hasRelatedWork W3641251 @default.
- W4239333556 hasRelatedWork W5350384 @default.
- W4239333556 hasRelatedWork W14574791 @default.
- W4239333556 isParatext "false" @default.
- W4239333556 isRetracted "false" @default.
- W4239333556 workType "book" @default.