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- W4239410236 abstract "A previously healthy 5-year-old girl presented with generalized weakness and “tingling.” The previous day, she had begun walking “like a drunk.” She was afebrile, could not stand without assistance, was areflexic, and cried that her extremities felt “asleep.” A tick found on the crown of her head was carefully removed and preserved. Within 12 hours of the tick's removal, the child was her normal, energetic self. Tick paralysis is caused by more than 40 species of ticks worldwide, including 5 in North America.1Grattan-Smith PJ Morris JG Johnston HM et al.Clinical and neurophysiological features of tick paralysis.Brain. 1997; 120: 1975-1987Crossref PubMed Scopus (136) Google Scholar Human cases typically occur in children younger than 10 years. Paralysis occurs when a gravid, feeding tick excretes a neurotoxin into its host.1Grattan-Smith PJ Morris JG Johnston HM et al.Clinical and neurophysiological features of tick paralysis.Brain. 1997; 120: 1975-1987Crossref PubMed Scopus (136) Google Scholar The neurotoxin's precise mechanism of action in humans remains obscure.2Vedanarayanan VV Evans OB Subramony SH Tick paralysis in children: electrophysiology and possibility of misdiagnosis.Neurology. 2002; 59: 1088-1090Crossref PubMed Scopus (39) Google Scholar Unlike Lyme disease, tick paralysis gradually resolves once the offending tick is removed.3Greenstein P Tick paralysis.Med Clin North Am. 2002; 86: 441-446Abstract Full Text Full Text PDF PubMed Scopus (31) Google Scholar Untreated tick paralysis may cause respiratory failure and death. Any child presenting with generalized, flaccid weakness should be examined thoroughly for a tick." @default.
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- W4239410236 date "2005-07-01" @default.
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- W4239410236 title "Tick Paralysis" @default.
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- W4239410236 doi "https://doi.org/10.4065/80.7.938" @default.
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