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• W4239432044 startingPage "606" @default.
• W4239432044 abstract "Localized scleroderma, also known as morphoea, has a variety of clinical manifestations that can include systemic involvement. Early recognition, diagnosis and treatment may improve the long-term outcome.A large multicentre study coordinated by the Pediatric Rheumatology European Society has yielded important information on the epidemiology and clinical manifestations of juvenile localized scleroderma, especially as it pertains to systemic manifestations. Previous results using methotrexate and corticosteroids have been confirmed. Studies on phototherapy have also demonstrated efficacy. A new immunomodulator, imiquimod, has shown promise in an initial case series.Studies over the past year highlight the wide range of extracutaneous manifestations and different forms of localized scleroderma and suggest that treatment may be beneficial." @default.
• W4239432044 created "2022-05-12" @default.
• W4239432044 creator A5070009221 @default.
• W4239432044 creator A5078753446 @default.
• W4239432044 date "2006-11-01" @default.
• W4239432044 modified "2023-10-18" @default.
• W4239432044 title "Localized scleroderma" @default.
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• W4239432044 doi "https://doi.org/10.1097/01.bor.0000245727.40630.c3" @default.
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