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- W4239548652 abstract "BACKGROUND AND OBJECTIVE:The frequency of extra-articular manifestations in rheumatoid arthritis (ExRA) differs from one country to another, so we investigated ExRA frequency in a well-defined hospital patient population with rheumatoid arthritis (RA) in Saudi Arabia. We also examined possible predictors of the development ExRA.METHODS:A retrospective analysis was conducted of all patients diagnosed with RA at a university hospital during a 4-year period. Cases were classified according to the 1987 American College of Rheumatology criteria for RA, and the frequency of ExRA was recorded.RESULTS:Of 140 patients who fulfilled the criteria for the diagnosis of RA, 98 (70%) developed ExRA features. Anemia occurred in 61%, thrombocytosis in 16%, pulmonary involvement in 10%, and renal amyloidosis, vasculitis and Felty syndrome were present in 6%, 2% and 1%, respectively. The mortality rate was high (16%) in patients with ExRA. The predictors for mortality were lung involvement, age over 50 years and kidney amyloidosis.CONCLUSION:ExRA were present in a substantial proportion of our patients, which lead to a worse disease outcome. Anemia, thrombocytosis and respiratory system involvement were the commonest. Early recognition and treatment are important to decrease mortality." @default.
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- W4239548652 date "2009-05-01" @default.
- W4239548652 modified "2023-10-16" @default.
- W4239548652 title "Extra-Articular Manifestations of Rheumatoid Arthritis: A Hospital-Based Study" @default.
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- W4239548652 doi "https://doi.org/10.5144/0256-4947.51774" @default.
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