Matches in SemOpenAlex for { <https://semopenalex.org/work/W4239596989> ?p ?o ?g. }
Showing items 1 to 57 of
57
with 100 items per page.
- W4239596989 endingPage "471" @default.
- W4239596989 startingPage "463" @default.
- W4239596989 abstract "Chlamydomonas reinhardtii activatesCpx1, Cyc6, and Crd1, encoding, respectively, coproporphyrinogen oxidase, cytochromec 6, and a novel di-iron enzyme when transferred to oxygen-deficient growth conditions. This response is physiologically relevant because C. reinhardtiiexperiences these growth conditions routinely, and furthermore, one of the target genes, Crd1, is functionally required for normal growth under oxygen-depleted conditions. The same genes are activated also in response to copper-deficiency through copper-response elements that function as target sites for a transcriptional activator. The core of the copper-response element, GTAC, is required also for the hypoxic response, as is a trans-acting locus, CRR1. Mercuric ions, which antagonize the copper-deficiency response, also antagonize the oxygen-deficiency response of these target genes. Taken together, these observations suggest that the oxygen- and copper-deficiency responses share signal transduction components. Nevertheless, whereas the copper-response element is sufficient for the nutritional copper response, the oxygen-deficiency response requires, in addition, a second cis-element, indicating that the response to oxygen depletion is not identical to the nutritional copper response. The distinction between the two responses is also supported by comparative analysis of the response of the target genes,Cyc6, Cpx1, and Crd1, to copper versus oxygen deficiency. A Crr1-independent pathway forHyd1 expression in oxygen-depleted C. reinhardtii demonstrates the existence of multiple oxygen/redox-responsive circuits in this model organism." @default.
- W4239596989 created "2022-05-12" @default.
- W4239596989 creator A5083478741 @default.
- W4239596989 date "2002-02-01" @default.
- W4239596989 modified "2023-09-27" @default.
- W4239596989 title "Oxygen Deficiency Responsive Gene Expression in Chlamydomonas reinhardtii through a Copper-Sensing Signal Transduction Pathway" @default.
- W4239596989 doi "https://doi.org/10.1104/pp.128.2.463" @default.
- W4239596989 hasPublicationYear "2002" @default.
- W4239596989 type Work @default.
- W4239596989 citedByCount "2" @default.
- W4239596989 crossrefType "journal-article" @default.
- W4239596989 hasAuthorship W4239596989A5083478741 @default.
- W4239596989 hasBestOaLocation W42395969891 @default.
- W4239596989 hasConcept C104317684 @default.
- W4239596989 hasConcept C143065580 @default.
- W4239596989 hasConcept C178790620 @default.
- W4239596989 hasConcept C185592680 @default.
- W4239596989 hasConcept C2777106986 @default.
- W4239596989 hasConcept C2777727519 @default.
- W4239596989 hasConcept C540031477 @default.
- W4239596989 hasConcept C544778455 @default.
- W4239596989 hasConcept C55493867 @default.
- W4239596989 hasConcept C62478195 @default.
- W4239596989 hasConcept C86803240 @default.
- W4239596989 hasConcept C95444343 @default.
- W4239596989 hasConceptScore W4239596989C104317684 @default.
- W4239596989 hasConceptScore W4239596989C143065580 @default.
- W4239596989 hasConceptScore W4239596989C178790620 @default.
- W4239596989 hasConceptScore W4239596989C185592680 @default.
- W4239596989 hasConceptScore W4239596989C2777106986 @default.
- W4239596989 hasConceptScore W4239596989C2777727519 @default.
- W4239596989 hasConceptScore W4239596989C540031477 @default.
- W4239596989 hasConceptScore W4239596989C544778455 @default.
- W4239596989 hasConceptScore W4239596989C55493867 @default.
- W4239596989 hasConceptScore W4239596989C62478195 @default.
- W4239596989 hasConceptScore W4239596989C86803240 @default.
- W4239596989 hasConceptScore W4239596989C95444343 @default.
- W4239596989 hasIssue "2" @default.
- W4239596989 hasLocation W42395969891 @default.
- W4239596989 hasOpenAccess W4239596989 @default.
- W4239596989 hasPrimaryLocation W42395969891 @default.
- W4239596989 hasRelatedWork W1972487430 @default.
- W4239596989 hasRelatedWork W1991623275 @default.
- W4239596989 hasRelatedWork W2023185610 @default.
- W4239596989 hasRelatedWork W2085057994 @default.
- W4239596989 hasRelatedWork W2093134088 @default.
- W4239596989 hasRelatedWork W2147636237 @default.
- W4239596989 hasRelatedWork W2171277769 @default.
- W4239596989 hasRelatedWork W2434392648 @default.
- W4239596989 hasRelatedWork W4241349829 @default.
- W4239596989 hasRelatedWork W4246000443 @default.
- W4239596989 hasVolume "128" @default.
- W4239596989 isParatext "false" @default.
- W4239596989 isRetracted "false" @default.
- W4239596989 workType "article" @default.