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- W4239618652 abstract "Streptomyces bacteria are the most important source of antibiotics. They are also among the most complex bacteria, growing as a network of filaments from which emerge aerial branches bearing chains of spores. Early genetic studies, starting in the 1950s, established a map of the Streptomyces coelicolor chromosome that included genes for antibiotic production and morphological development. Most of these genes were cloned in the 1980s and 1990s, providing a biological context that has maximized the value of the twenty-first-century genome sequencing, with its attendant ‘-omic’ technologies. Now, hundreds of antibiotic biosynthetic gene clusters are being studied and engineered with the hope of therapeutic benefits, and the diverse currents of Streptomyces research are beginning to come together to give an integrated molecular picture of these remarkable organisms." @default.
- W4239618652 created "2022-05-12" @default.
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- W4239618652 date "2013-01-01" @default.
- W4239618652 modified "2023-10-14" @default.
- W4239618652 title "Streptomyces" @default.
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- W4239618652 doi "https://doi.org/10.1016/b978-0-12-374984-0.01483-2" @default.
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