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- W4239772011 abstract "The Amiga 3000 is nearly ideal for desktop molecular modeling. It uses the Motorola 68030 32-bit processor, running at 16 or 25 MHz, with either the 68881 or 68882 math coprocessor and eight custom processing chips. The video system is NTSC compatible 15.75- or 31.5-KHzRGB analog or digital. The system video interface offers user selectable 320 × 200, 640 × 480. 768 × 480 or 1280 × 400 resolution with a displayable palette of 4 096 colors and interlaced, noninterlaced and overscan modes. NTSC compatibility permits simple and inexpensive video signal synchronization, so that composed monitor images can be displayed and recorded with standard video equipment. The processor, in conjunction with the custom video chips, can manipulate models mathematically at a sufficient rate to present moving or animated images in real time. Users can interact with the molecular image with mouse or joystick controls. A third-party manufacturer, Haitex Resources, has produced an inexpensive stereo image display interface for the Amiga. This stereo image display system consists of liquid crystal shutter goggles attached to a control module on one mouse/joystick port and synchronized at 60 Hz with alternating left/right screen displays.Several simple molecular graphics programs for the Amiga have been available in the public domain since 1988. The ease of video interfacing and the availability of stereo image display have stimulated several developers to begin assembling molecular modeling packages. At the National Biomedical Research Foundation the Amiga is being tested as an inexpensive stereo-image color graphics workstation for molecular modeling, biopolymer sequence analysis and medical imaging. We hope to use it as a prototyping system for program development and testing, with a large cost savings over graphics display processors. We are seeking to incorporate secondary and tertiary structural considerations into the process of aligning distantly related proteins. This would enable us to make alignments that have a much higher probability of representing accurately the evolutionary relationship of two proteins, the structural relationship of antigenic sites, or the functional relationship of related domains in different proteins. The stereo-image display capabilities of the Amiga allow us to align sequences to known tertiary structures of related sequences. The Amiga's software portability and networking capabilities allow us to use the tested software on other, more expensive computers. Its stereo-image graphics display capabilities provide an essential tool for examining the tertiary structure and functional domains of proteins and for investigating the relationships between genetic expression, protein sequence, protein structure and protein function." @default.
- W4239772011 created "2022-05-12" @default.
- W4239772011 date "1987-06-01" @default.
- W4239772011 modified "2023-09-30" @default.
- W4239772011 title "Enter the 68030" @default.
- W4239772011 doi "https://doi.org/10.1016/0141-9331(87)90287-0" @default.
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