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- W4239782053 abstract "This chapter talks about lipofuscin. Lipofuscin comes from a Greek word, “lipo” that means “fat” and a Latin word, “fuscus” which means “dusky” or “dark”. Hence, lipofuscin is a “dark”, “dusky” or “pigmented” lipid. The word is often carelessly mispronounced and sometimes misprinted as “lipofuchsin.” This pigment appears yellowish-brown under the microscope, it stains intensely with basophilic dyes, it is acid fast and fluoresces yellow-green to orange under ultraviolet light. It is also sudanophilic, periodic acid-Schiff reagent (PAS) positive and shows electron dense osmiophilic granules under the electron microscope. Lipofuscin is found in organs other than the central nervous system. It was described in cardiac muscle as long ago as by Goldenberg and by Opie. Lipofuscin has also been recorded in skeletal muscle, voluntary muscle, liver, adrenals and other organs and tissues of the body particularly in fat tissue. According to some authors ceroid and lipofuscin display the same physical and biological characteristics at sometime in their evolution. Ceroid is commonly found in vitamin E deficient animals. There is evidence from light microscopy, solubility, auto-fluorescence, chemical properties and ultrastructure that suggests that lipofuscin and ceroid are the same pigments." @default.
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- W4239782053 date "1973-01-01" @default.
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- W4239782053 title "Lipofuscin" @default.
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- W4239782053 doi "https://doi.org/10.1016/s0079-6123(08)60687-1" @default.
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