Matches in SemOpenAlex for { <https://semopenalex.org/work/W4239935834> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W4239935834 endingPage "531" @default.
- W4239935834 startingPage "531" @default.
- W4239935834 abstract "Intraperitoneal LD50 (lethal dose 50% kill) values and minimal liver toxic doses in female Sprague-Dawley rats were determined for the following industrial solvents: toluene, methylene chloride, carbon tetrachloride, 1,1,1-trichloroethane, 1,1,2-trichloroethane, trichloroethylene, ethanol, methyl ethyl ketone, and dioxane. For the following solvents LC50 values and minimal liver toxic air concentrations were also determined: xylene, styrene, chloroform, tetrachloroethylene, and dimethylformamide (DMF). The serum activity of the enzyme sorbitol dehydrogenase (SDH) was used as an indicator of liver damage. Carbon tetrachloride, chloroform, and DMF were hepatotoxic in low doses compared to LD50 values (TD50 (toxic dose 50%) values approximately 30, 90, and 50 mg/kg). Chloroform and DMF were hepatotoxic in comparatively low concentrations after a 4-hr inhalation exposure (TC50 (toxic concentration 50%) values approximately 590 and 740 mg/m3). Even relatively high doses of the other solvents did not raise the SDH activity. Significant direct (metabolite-mediated) hepatotoxicity seems to be an uncommon feature among commonly used industrial solvents." @default.
- W4239935834 created "2022-05-12" @default.
- W4239935834 date "1965-01-01" @default.
- W4239935834 modified "2023-09-26" @default.
- W4239935834 title "816. Two-way traffic" @default.
- W4239935834 doi "https://doi.org/10.1016/s0015-6264(65)80162-6" @default.
- W4239935834 hasPublicationYear "1965" @default.
- W4239935834 type Work @default.
- W4239935834 citedByCount "0" @default.
- W4239935834 crossrefType "journal-article" @default.
- W4239935834 hasConcept C13965031 @default.
- W4239935834 hasConcept C178790620 @default.
- W4239935834 hasConcept C181199279 @default.
- W4239935834 hasConcept C185592680 @default.
- W4239935834 hasConcept C2777359374 @default.
- W4239935834 hasConcept C2777477808 @default.
- W4239935834 hasConcept C2777712214 @default.
- W4239935834 hasConcept C2777905771 @default.
- W4239935834 hasConcept C2778142098 @default.
- W4239935834 hasConcept C2778695967 @default.
- W4239935834 hasConcept C2779404209 @default.
- W4239935834 hasConcept C2779896714 @default.
- W4239935834 hasConcept C2780371127 @default.
- W4239935834 hasConcept C2780400988 @default.
- W4239935834 hasConcept C2780471494 @default.
- W4239935834 hasConcept C2781144210 @default.
- W4239935834 hasConcept C33070731 @default.
- W4239935834 hasConcept C43617362 @default.
- W4239935834 hasConcept C55493867 @default.
- W4239935834 hasConcept C86803240 @default.
- W4239935834 hasConceptScore W4239935834C13965031 @default.
- W4239935834 hasConceptScore W4239935834C178790620 @default.
- W4239935834 hasConceptScore W4239935834C181199279 @default.
- W4239935834 hasConceptScore W4239935834C185592680 @default.
- W4239935834 hasConceptScore W4239935834C2777359374 @default.
- W4239935834 hasConceptScore W4239935834C2777477808 @default.
- W4239935834 hasConceptScore W4239935834C2777712214 @default.
- W4239935834 hasConceptScore W4239935834C2777905771 @default.
- W4239935834 hasConceptScore W4239935834C2778142098 @default.
- W4239935834 hasConceptScore W4239935834C2778695967 @default.
- W4239935834 hasConceptScore W4239935834C2779404209 @default.
- W4239935834 hasConceptScore W4239935834C2779896714 @default.
- W4239935834 hasConceptScore W4239935834C2780371127 @default.
- W4239935834 hasConceptScore W4239935834C2780400988 @default.
- W4239935834 hasConceptScore W4239935834C2780471494 @default.
- W4239935834 hasConceptScore W4239935834C2781144210 @default.
- W4239935834 hasConceptScore W4239935834C33070731 @default.
- W4239935834 hasConceptScore W4239935834C43617362 @default.
- W4239935834 hasConceptScore W4239935834C55493867 @default.
- W4239935834 hasConceptScore W4239935834C86803240 @default.
- W4239935834 hasLocation W42399358341 @default.
- W4239935834 hasOpenAccess W4239935834 @default.
- W4239935834 hasPrimaryLocation W42399358341 @default.
- W4239935834 hasRelatedWork W1973369921 @default.
- W4239935834 hasRelatedWork W1986233789 @default.
- W4239935834 hasRelatedWork W1997692020 @default.
- W4239935834 hasRelatedWork W1998355359 @default.
- W4239935834 hasRelatedWork W2000782266 @default.
- W4239935834 hasRelatedWork W2006431949 @default.
- W4239935834 hasRelatedWork W2052069794 @default.
- W4239935834 hasRelatedWork W2320653240 @default.
- W4239935834 hasRelatedWork W2349201439 @default.
- W4239935834 hasRelatedWork W2489575574 @default.
- W4239935834 hasVolume "3" @default.
- W4239935834 isParatext "false" @default.
- W4239935834 isRetracted "false" @default.
- W4239935834 workType "article" @default.