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• W4240051608 abstract "The antimutagenic potencies of the juices of 28 fruits and 34 vegetables commonly consumed in Germany were investigated with respect to the mutagenic activities induced by 2-amino-3-methyl[4,5-f]quinoline (IQ), and in part by 2-amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ) or 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in Salmonella typhimurium TA98 and TA100. With IQ, weak to strong antimutagenic activities were found in 68% of the fruits and 73% of the vegetables that were tested. In fruits, strong antimutagenic activities were detected in bananas, blackberries, blueberries, sweet and sour cherries, blackcurrants and redcurrants, pineapple and watermelon. Moderate antimutagenic activities were detected in greenage, kiwi, mangos, honeydew melons and plums. Weak antimutagenic activities were detected in apple, apricot, mirabelle, pears, peaches and strawberries, whereas white and red grapes and raspberries were inactive, and gooseberries and citrus fruits in general possessed marginal or no antimutagenic activities. In vegetables, strong to moderate antimutagenic activities were found for all cruciferous vegetables, except Chinese cabbage, which had only weak antimutagenic activity. Other vegetables with strong antimutagenic activities were beets, chives, horseradish, onions, rhubarb and spinach. Moderate antimutagenic activities were found with green beans and tomatoes, weak activities in eggplant, garden cress, many lettuces, leeks, mangold, cucumber, pumpkin, radish and summer squash. Asparagus, carrots, fennel leaves, parsley, green peppers and radishes were inactive. When fruit and vegetable juices were heated, a considerable reduction of antimutagenic potencies was seen with apple, apricot, kiwi, pineapple, beets, cabbage (Chinese, Savoy, red and white), cauliflower, leafy lettuce, cucumber, onions, radish and rhubarb. Antimutagenic factors in blackberries, blueberries, sweet and sour cherries, honeydew melons, mirabelle, plums, strawberries. Brussels sprouts, chicory greens, eggplant, garden cress, mangold, pumpkin, lamb's lettuce and spinach were, however, remarkably heat stable. Antimutagenic potencies in bananas, blackcurrants and redcurrants, greengages, gooseberries, mangos, watermelon, green beans, kohlrabi, horseradish, tomatoes and chives were partially reduced. Antimutagenic activities in the juices of eight apple cultivars were moderate in two, weak in four, and marginal or absent in two. No major differences, however, were detected in five batches of oranges and three batches each of grapefruits, asparagus, green beans, broccoli, cauliflower, spinach and tomatoes. No (or only minor) differences were seen between IQ, MeIQ and McIQx and tester strains TA98 and TA100. Pineapple and celeriac juices inhibited the enzymatic system responsible for the activation of IQ, but had no desmutagenic activity. Peroxidase activity found to be present in broccoli, cauliflower, green beans and tomatoes may contribute to antimutagenic activities in these vegetables." @default.
• W4240051608 created "2022-05-12" @default.
• W4240051608 date "1945-01-01" @default.
• W4240051608 modified "2023-09-27" @default.
• W4240051608 title "South Pacific garden is weedless" @default.
• W4240051608 doi "https://doi.org/10.1016/0016-0032(45)90432-7" @default.
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