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- W4240168978 abstract "At the leading edge: Chiral fluoromalonates can be prepared with very high stereocontrol by enantioselective fluorination of racemic malonates and using a Zn(OAc)2/DBFOXPh catalyst (see scheme), thus providing an efficient alternative route to conventional microbial desymmetrization for the preparation of fluorinated chiral building blocks. Several pharmaceutically attractive compounds were prepared by using this method. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2008/z704093_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article." @default.
- W4240168978 created "2022-05-12" @default.
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- W4240168978 date "2007-12-13" @default.
- W4240168978 modified "2023-10-18" @default.
- W4240168978 title "Desymmetrization-like Catalytic Enantioselective Fluorination of Malonates and Its Application to Pharmaceutically Attractive Molecules" @default.
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- W4240168978 doi "https://doi.org/10.1002/anie.200704093" @default.
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