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- W4240351259 endingPage "2937" @default.
- W4240351259 startingPage "2926" @default.
- W4240351259 abstract "The gene for an essential protein subunit of nuclear RNase P from Saccharomyces cerevisiae has been cloned. The gene for this protein, RPP1, was identified by virtue of its homology with a human scleroderma autoimmune antigen, Rpp30, which copurifies with human RNase P. Epitope-tagged Rpp1 can be found in association with both RNase P RNA and a related endoribonuclease, RNase MRP RNA, in immunoprecipitates from crude extracts of cells. Depletion of Rpp1 in vivo leads to the accumulation of precursor tRNAs with unprocessed 5' and 3' termini and reveals rRNA processing defects that have not been described previously for proteins associated with RNase P or RNase MRP. Immunoprecipitated complexes cleave both yeast precursor tRNAs and precursor rRNAs." @default.
- W4240351259 created "2022-05-12" @default.
- W4240351259 creator A5002470142 @default.
- W4240351259 creator A5003873129 @default.
- W4240351259 date "1997-11-01" @default.
- W4240351259 modified "2023-10-16" @default.
- W4240351259 title "Rpp1, an essential protein subunit of nuclear RNase P required for processing of precursor tRNA and 35S precursor rRNA in<i>Saccharomyces cerevisiae</i>" @default.
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- W4240351259 doi "https://doi.org/10.1101/gad.11.21.2926" @default.
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