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- W4240437010 abstract "The recent identification of genetic diseases (incontinentia pigmenti, anhidrotic ectodermal dysplasia with immunodeficiency and cylindromatosis) resulting from mutations affecting components of the nuclear factor-κB (NF-κB) signaling pathway provides a unique opportunity to understand the function of NF-κB in vivo. Besides confirming the importance of NF-κB in innate and acquired immunity or bone mass control, analysis of these diseases has uncovered new critical roles played by this transcription factor in the development and homeostasis of the epidermis and the proper function of lymphatic vessels. In addition, the identified mutations will help understanding at the molecular level how NF-κB is activated in response to cell stimulation." @default.
- W4240437010 created "2022-05-12" @default.
- W4240437010 creator A5036864831 @default.
- W4240437010 creator A5037502253 @default.
- W4240437010 date "2006-01-06" @default.
- W4240437010 modified "2023-10-13" @default.
- W4240437010 title "NF-κB-related genetic diseases" @default.
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- W4240437010 doi "https://doi.org/10.1038/sj.cdd.4401841" @default.
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