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- W4240484996 abstract "Reply: The four points posed by Dr B. A. Cotton and colleagues constitute the second paragraph of our reply (1), which emphasize the difficulties in the cognitive assessment in sedated and mechanically ventilated intensive care unit patients and refer to the whole number of studies dealing with the issue of delirium development in hospitalized patients. We have no intention at all of contradicting or even questioning the studies by Dr Ely's group, whose expertise on the subject cannot in any way be doubted, and we apologize that in our reply, we did not specify that delirium assessment may not be applicable to deeply sedated patients. In our study (2), in most of the intensive care unit patients, delirium could not be diagnosed because of the severity of illness and the presence of shock requiring deep sedation. Because we have not included the delirium assessment in this study, the answer to the question whether there is a relation between serum S100B protein and delirium development remains to be resolved in a future study. Christina Routsi Elizabeth Stamataki Seraphim Nanas Charis Roussos Medical School of Athens University Evangelismos Hospital Athens, Greece" @default.
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- W4240484996 date "2008-08-01" @default.
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- W4240484996 title "Increased levels of serum S100B protein in critically ill patients without brain injury" @default.
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- W4240484996 doi "https://doi.org/10.1097/shk.0b013e318162c881" @default.
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