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- W4240517504 abstract "Selektiv aktiviert werden Galactosid-Prodrugs durch lysosomale β-Galactosidase im Inneren von Krebszellen, die einen spezifischen tumorassoziierten Rezeptor exprimieren. Dieser effiziente enzymatische Prozess führt zu einer starken cytotoxischen Wirkung, weil das Antimitotikum MMAE freigesetzt wird, und ermöglicht die Zerstörung von Tumorzellen mit dem Rezeptor sowie von benachbarten Tumorzellen ohne Rezeptor." @default.
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- W4240517504 date "2012-09-20" @default.
- W4240517504 modified "2023-10-18" @default.
- W4240517504 title "The First Generation of β-Galactosidase-Responsive Prodrugs Designed for the Selective Treatment of Solid Tumors in Prodrug Monotherapy" @default.
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