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- W4240561265 abstract "Mice at 18 weeks of age underwent an unpredictable chronic mild stress (UCMS; 5 days/week for 7 hrs/day) paradigm to elicit a chronically stressed phenotype. Control and stressed mice underwent 8 weeks of nitrite supplementation (50mg/L) within their drinking water. At 26 weeks, mice were euthanized, and the thoracic aortas were removed and positioned in a wire myograph chamber. To assess vessel health, the aortas were precontracted with U46619 (7.5x10-9M) and exposed to increasing concentrations of methacholine (MCh; 10-9M to 10-5M) and sodium nitroprusside (SNP; 10-9M to 10-5M). Aortic intrinsic mechanical stiffness and carotid pulse wave velocity were further measured. IHC staining of abdominal aorta was conducted for total collagen and medial elastin content." @default.
- W4240561265 created "2022-05-12" @default.
- W4240561265 creator A5066650633 @default.
- W4240561265 date "2021-08-06" @default.
- W4240561265 modified "2023-09-29" @default.
- W4240561265 title "Nitrite Supplementation Restores Aortic Health in Chronically Stressed Mice" @default.
- W4240561265 doi "https://doi.org/10.33915/etd.8265" @default.
- W4240561265 hasPublicationYear "2021" @default.
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