Matches in SemOpenAlex for { <https://semopenalex.org/work/W4240585898> ?p ?o ?g. }
- W4240585898 endingPage "143" @default.
- W4240585898 startingPage "112" @default.
- W4240585898 abstract "Glycosylation is one of the most important posttranslational modifications of proteins. In addition to cell-surface proteins, many intracellular proteins, such as cytoplasmic, nuclear and mitochondrial proteins, are also glycosylated. The intracellular glycosylation processes are adjusted by different functionally specific glycosyltransferases and glycosidases. Among the various intracellular glycosylation processes, O-GlcNAcylation and sialylation are two main types that play critical roles in the regulation of the structure, function and localization of proteins. Hence visualization of intracellular glycosylation is of great importance for revealing glycosylation-related biological processes. Owing to the complicated intracellular environment, visualization of intracellular glycosylation processes is a great challenge. By utilizing glycan labelling methods and glycol–enzyme-induced fluorescence resonance energy transfer (FRET) or competitive binding, preliminary visualization of intracellular O-GlcNAcylation- and sialylation-related enzyme activities has been achieved. This chapter presents a detailed description of current methods developed for the visualization of intracellular glycosylation, including the design and preparation of glycan-recognizable probes, protein labelling and signal switches. Future developments should be focused on the fabrication of biomimetic molecular probes with novel recognition mechanisms and the glycosylation events in specific organelles require more investigation." @default.
- W4240585898 created "2022-05-12" @default.
- W4240585898 date "2020-01-28" @default.
- W4240585898 modified "2023-09-24" @default.
- W4240585898 title "Visualization of Intracellular Glycosylation" @default.
- W4240585898 cites W1480650704 @default.
- W4240585898 cites W1482074571 @default.
- W4240585898 cites W1508805699 @default.
- W4240585898 cites W1563881139 @default.
- W4240585898 cites W1568866400 @default.
- W4240585898 cites W1575380345 @default.
- W4240585898 cites W1591752816 @default.
- W4240585898 cites W1826433977 @default.
- W4240585898 cites W1938656015 @default.
- W4240585898 cites W1965353927 @default.
- W4240585898 cites W1969939865 @default.
- W4240585898 cites W1970662326 @default.
- W4240585898 cites W1974742351 @default.
- W4240585898 cites W1975320495 @default.
- W4240585898 cites W1982777272 @default.
- W4240585898 cites W1984827962 @default.
- W4240585898 cites W1987496643 @default.
- W4240585898 cites W1988504408 @default.
- W4240585898 cites W1989730031 @default.
- W4240585898 cites W1994644330 @default.
- W4240585898 cites W1995681224 @default.
- W4240585898 cites W1996786134 @default.
- W4240585898 cites W1998906741 @default.
- W4240585898 cites W2002062311 @default.
- W4240585898 cites W2007838251 @default.
- W4240585898 cites W2008028087 @default.
- W4240585898 cites W2021461446 @default.
- W4240585898 cites W2030730002 @default.
- W4240585898 cites W2031087463 @default.
- W4240585898 cites W2032583642 @default.
- W4240585898 cites W2039547504 @default.
- W4240585898 cites W2040170958 @default.
- W4240585898 cites W2040605299 @default.
- W4240585898 cites W2040714286 @default.
- W4240585898 cites W2041967294 @default.
- W4240585898 cites W2048470673 @default.
- W4240585898 cites W2049815567 @default.
- W4240585898 cites W2050560857 @default.
- W4240585898 cites W2056711756 @default.
- W4240585898 cites W2057151160 @default.
- W4240585898 cites W2059027410 @default.
- W4240585898 cites W2059725389 @default.
- W4240585898 cites W2060744329 @default.
- W4240585898 cites W2061385217 @default.
- W4240585898 cites W2069454964 @default.
- W4240585898 cites W2071163714 @default.
- W4240585898 cites W2075324784 @default.
- W4240585898 cites W2075995015 @default.
- W4240585898 cites W2077858856 @default.
- W4240585898 cites W2079351904 @default.
- W4240585898 cites W2079463341 @default.
- W4240585898 cites W2085309586 @default.
- W4240585898 cites W2085677500 @default.
- W4240585898 cites W2085709003 @default.
- W4240585898 cites W2090942673 @default.
- W4240585898 cites W2101298061 @default.
- W4240585898 cites W2107601138 @default.
- W4240585898 cites W2114185395 @default.
- W4240585898 cites W2116227340 @default.
- W4240585898 cites W2119363781 @default.
- W4240585898 cites W2125292310 @default.
- W4240585898 cites W2128057497 @default.
- W4240585898 cites W2130286351 @default.
- W4240585898 cites W2132563940 @default.
- W4240585898 cites W2135199552 @default.
- W4240585898 cites W2136024887 @default.
- W4240585898 cites W2138183388 @default.
- W4240585898 cites W2140853226 @default.
- W4240585898 cites W2142001232 @default.
- W4240585898 cites W2154008781 @default.
- W4240585898 cites W2158502376 @default.
- W4240585898 cites W2158558808 @default.
- W4240585898 cites W2164246113 @default.
- W4240585898 cites W2233739953 @default.
- W4240585898 cites W2313332578 @default.
- W4240585898 cites W2321081523 @default.
- W4240585898 cites W2322691084 @default.
- W4240585898 cites W2786227026 @default.
- W4240585898 cites W4250609434 @default.
- W4240585898 cites W632569742 @default.
- W4240585898 cites W2528874153 @default.
- W4240585898 doi "https://doi.org/10.1039/9781839160455-00112" @default.
- W4240585898 hasPublicationYear "2020" @default.
- W4240585898 type Work @default.
- W4240585898 citedByCount "0" @default.
- W4240585898 crossrefType "book-chapter" @default.
- W4240585898 hasConcept C108625454 @default.
- W4240585898 hasConcept C121332964 @default.
- W4240585898 hasConcept C185592680 @default.
- W4240585898 hasConcept C190062978 @default.
- W4240585898 hasConcept C206212055 @default.
- W4240585898 hasConcept C2777313579 @default.
- W4240585898 hasConcept C55493867 @default.