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• W4240683909 abstract "To the Editor:We read with great interest the recent article in CHEST (November 2008) by Wynn and colleagues1Wynn GJ Turkington PM O'Driscoll BR Anthracofibrosis, bronchial stenosis with overlying anthracotic mucosa: possibly a new occupational lung disorder; a series of seven cases from one UK hospital.Chest. 2008; 134: 1069-1073Abstract Full Text Full Text PDF PubMed Scopus (42) Google Scholar reporting on patients with anthracofibrosis, possibly due to occupational exposure. Anthracofibrosis is defined as a narrowing of the bronchial lumen with overlying anthracotic mucosa that is most frequently attributed to tuberculosis.2Chung MP Lee KS Han J et al.Bronchial stenosis due to anthracofibrosis.Chest. 1998; 113: 344-350Abstract Full Text Full Text PDF PubMed Scopus (132) Google Scholar The authors described six patients with anthracofibrosis without a history of tuberculosis but with a history of occupational exposure. The patients were exposed to coal dust and other dust known to induce bronchial mucosa black tattoos. The occurrence of anthracofibrosis with bronchial narrowing suggests an extreme manifestation of tattoos due to dust exposure.In a recent article,3Naccache JM Monnet I Nunes H et al.Anthracofibrosis attributed to mixed mineral dust exposure: report of three cases.Thorax. 2008; 63: 655-657Crossref PubMed Scopus (0) Google Scholar we described three patients with anthracofibrosis that was attributed to mixed mineral dust exposure. None of the patients had a history of tuberculosis. They had experienced occupational exposure to silica, silica and aluminum, and silica and asphalt. Mineralogical analysis by transmission electron microscopy of BAL fluid, pulmonary, hilar, or bronchial samples found high levels of particle retention. Two patients had high percentages of free crystalline silica and mica, and the third patient had high percentages of free crystalline silica, kaolin, and other silicates. These findings suggested that mixed mineral dust was the cause of the anthracofibrosis.Together with our observations, the article by Wynn et al1Wynn GJ Turkington PM O'Driscoll BR Anthracofibrosis, bronchial stenosis with overlying anthracotic mucosa: possibly a new occupational lung disorder; a series of seven cases from one UK hospital.Chest. 2008; 134: 1069-1073Abstract Full Text Full Text PDF PubMed Scopus (42) Google Scholar strengthens the link between occupational exposure and anthracofibrosis. In patients with authracofibrosis, the taking of a detailed history of potential exposures is critical. We would like to emphasize that exposures other than those to coal could lead to anthracofibrosis. Moreover, mineralogical analysis can identify the presence of causative mineral dusts. To the Editor: We read with great interest the recent article in CHEST (November 2008) by Wynn and colleagues1Wynn GJ Turkington PM O'Driscoll BR Anthracofibrosis, bronchial stenosis with overlying anthracotic mucosa: possibly a new occupational lung disorder; a series of seven cases from one UK hospital.Chest. 2008; 134: 1069-1073Abstract Full Text Full Text PDF PubMed Scopus (42) Google Scholar reporting on patients with anthracofibrosis, possibly due to occupational exposure. Anthracofibrosis is defined as a narrowing of the bronchial lumen with overlying anthracotic mucosa that is most frequently attributed to tuberculosis.2Chung MP Lee KS Han J et al.Bronchial stenosis due to anthracofibrosis.Chest. 1998; 113: 344-350Abstract Full Text Full Text PDF PubMed Scopus (132) Google Scholar The authors described six patients with anthracofibrosis without a history of tuberculosis but with a history of occupational exposure. The patients were exposed to coal dust and other dust known to induce bronchial mucosa black tattoos. The occurrence of anthracofibrosis with bronchial narrowing suggests an extreme manifestation of tattoos due to dust exposure. In a recent article,3Naccache JM Monnet I Nunes H et al.Anthracofibrosis attributed to mixed mineral dust exposure: report of three cases.Thorax. 2008; 63: 655-657Crossref PubMed Scopus (0) Google Scholar we described three patients with anthracofibrosis that was attributed to mixed mineral dust exposure. None of the patients had a history of tuberculosis. They had experienced occupational exposure to silica, silica and aluminum, and silica and asphalt. Mineralogical analysis by transmission electron microscopy of BAL fluid, pulmonary, hilar, or bronchial samples found high levels of particle retention. Two patients had high percentages of free crystalline silica and mica, and the third patient had high percentages of free crystalline silica, kaolin, and other silicates. These findings suggested that mixed mineral dust was the cause of the anthracofibrosis. Together with our observations, the article by Wynn et al1Wynn GJ Turkington PM O'Driscoll BR Anthracofibrosis, bronchial stenosis with overlying anthracotic mucosa: possibly a new occupational lung disorder; a series of seven cases from one UK hospital.Chest. 2008; 134: 1069-1073Abstract Full Text Full Text PDF PubMed Scopus (42) Google Scholar strengthens the link between occupational exposure and anthracofibrosis. In patients with authracofibrosis, the taking of a detailed history of potential exposures is critical. We would like to emphasize that exposures other than those to coal could lead to anthracofibrosis. Moreover, mineralogical analysis can identify the presence of causative mineral dusts." @default.
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• W4240683909 date "2009-06-01" @default.
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• W4240683909 title "Occupational Anthracofibrosis" @default.
• W4240683909 cites W1975413891 @default.
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• W4240683909 doi "https://doi.org/10.1378/chest.08-2864" @default.
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