FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4241288183> ?p ?o ?g. }

• W4241288183 endingPage "381" @default.
• W4241288183 startingPage "379" @default.
• W4241288183 abstract "Local anesthetics can produce pain during skin infiltration.We designed a randomized, prospective trial to determine whether needle gauge and/or solution pH affect pain during the intradermal infiltration of lidocaine. After approval by our institution's human studies review board, 40 healthy adult volunteers gave their consent to participate in this study. All of the volunteers randomly received four intradermal injections. Each volunteer was blinded as to the content of the intradermal injections and to which needle size was used for each injection. Each volunteer randomly received a 0.25-mL intradermal injection of the following four solutions: 1) lidocaine 2% administered through a 25-gauge needle (lido-25); 2) lidocaine 2% mixed with sodium bicarbonate (4 mL of 2% lidocaine plus 1 mL of sodium bicarbonate, pH 7.26) administered through a 25-gauge needle (lido-bicarb-25); 3) lidocaine 2% administered through a 30-gauge needle (lido-30); and 4) lidocaine 2% mixed with sodium bicarbonate (4 mL of 2% lidocaine plus 1 mL of sodium bicarbonate) administered through a 30-gauge needle (lido-bicarb-30). In each patient, the injection site was in the same region for each of the four injections. The skin wheal was tested for appropriate anesthesia using a 19-gauge needle on the skin wheal. A visual analog pain score was recorded after each intradermal injection. The pain scores were significantly higher in the lido-25 (3.2 +/- 0.2) group than in the lido-30 (2.5 +/- 0.3), lido-bicarb-25 (1.9 +/- 0.2), and lido-bicarb-30 (1.3 +/- 0.2) groups. The lido-bicarb-30 injection was also rated as less painful than the lido-30 injection. We found no differences between the lido-bicarb-25 and the lido-bicarb-30 injections. Complete analgesia for the 19-gauge needle pain stimulus was achieved in all patients for each injection. We conclude that, overall, the pain intensity of an intradermal injection of 2% lidocaine is low. The addition of sodium bicarbonate to 2% lidocaine decreases the pain associated with an intradermal skin wheal, and although the use of a 30-gauge needle decreases the pain of injection, the addition of sodium bicarbonate seems to have a greater overall effect than needle size. Implications: Forty volunteers randomly received four intradermal injections consisting of 2% lidocaine with or without sodium bicarbonate via a 25- or 30-gauge needle. The addition of bicarbonate had a greater overall effect than needle size in decreasing the pain associated with the intradermal injection of lidocaine. (Anesth Analg 1998;86:379-81)" @default.
• W4241288183 created "2022-05-12" @default.
• W4241288183 creator A5001328248 @default.
• W4241288183 creator A5032078009 @default.
• W4241288183 creator A5041924340 @default.
• W4241288183 date "1998-02-01" @default.
• W4241288183 modified "2023-10-02" @default.
• W4241288183 title "The Effect of Needle Gauge and Lidocaine pH on Pain During Intradermal Injection" @default.
• W4241288183 cites W1981983364 @default.
• W4241288183 cites W1992702723 @default.
• W4241288183 cites W2002220155 @default.
• W4241288183 cites W2041573443 @default.
• W4241288183 cites W2062119589 @default.
• W4241288183 cites W2073859076 @default.
• W4241288183 cites W2078429069 @default.
• W4241288183 cites W2092181988 @default.
• W4241288183 cites W2106266041 @default.
• W4241288183 cites W2158910673 @default.
• W4241288183 cites W2320326651 @default.
• W4241288183 cites W4300865841 @default.
• W4241288183 doi "https://doi.org/10.1213/00000539-199802000-00030" @default.
• W4241288183 hasPublicationYear "1998" @default.
• W4241288183 type Work @default.
• W4241288183 citedByCount "59" @default.
• W4241288183 countsByYear W42412881832012 @default.
• W4241288183 countsByYear W42412881832013 @default.
• W4241288183 countsByYear W42412881832015 @default.
• W4241288183 countsByYear W42412881832016 @default.
• W4241288183 countsByYear W42412881832017 @default.
• W4241288183 countsByYear W42412881832018 @default.
• W4241288183 countsByYear W42412881832019 @default.
• W4241288183 countsByYear W42412881832020 @default.
• W4241288183 countsByYear W42412881832021 @default.
• W4241288183 countsByYear W42412881832022 @default.
• W4241288183 countsByYear W42412881832023 @default.
• W4241288183 crossrefType "journal-article" @default.
• W4241288183 hasAuthorship W4241288183A5001328248 @default.
• W4241288183 hasAuthorship W4241288183A5032078009 @default.
• W4241288183 hasAuthorship W4241288183A5041924340 @default.
• W4241288183 hasBestOaLocation W42412881831 @default.
• W4241288183 hasConcept C141071460 @default.
• W4241288183 hasConcept C147789679 @default.
• W4241288183 hasConcept C185592680 @default.
• W4241288183 hasConcept C203014093 @default.
• W4241288183 hasConcept C2776420369 @default.
• W4241288183 hasConcept C2776768635 @default.
• W4241288183 hasConcept C2777397205 @default.
• W4241288183 hasConcept C2778937273 @default.
• W4241288183 hasConcept C2780149897 @default.
• W4241288183 hasConcept C42219234 @default.
• W4241288183 hasConcept C6557445 @default.
• W4241288183 hasConcept C71924100 @default.
• W4241288183 hasConcept C86803240 @default.
• W4241288183 hasConceptScore W4241288183C141071460 @default.
• W4241288183 hasConceptScore W4241288183C147789679 @default.
• W4241288183 hasConceptScore W4241288183C185592680 @default.
• W4241288183 hasConceptScore W4241288183C203014093 @default.
• W4241288183 hasConceptScore W4241288183C2776420369 @default.
• W4241288183 hasConceptScore W4241288183C2776768635 @default.
• W4241288183 hasConceptScore W4241288183C2777397205 @default.
• W4241288183 hasConceptScore W4241288183C2778937273 @default.
• W4241288183 hasConceptScore W4241288183C2780149897 @default.
• W4241288183 hasConceptScore W4241288183C42219234 @default.
• W4241288183 hasConceptScore W4241288183C6557445 @default.
• W4241288183 hasConceptScore W4241288183C71924100 @default.
• W4241288183 hasConceptScore W4241288183C86803240 @default.
• W4241288183 hasIssue "2" @default.
• W4241288183 hasLocation W42412881831 @default.
• W4241288183 hasLocation W42412881832 @default.
• W4241288183 hasOpenAccess W4241288183 @default.
• W4241288183 hasPrimaryLocation W42412881831 @default.
• W4241288183 hasRelatedWork W1978388898 @default.
• W4241288183 hasRelatedWork W2016852239 @default.
• W4241288183 hasRelatedWork W2057813089 @default.
• W4241288183 hasRelatedWork W2088461883 @default.
• W4241288183 hasRelatedWork W2093822913 @default.
• W4241288183 hasRelatedWork W2171414941 @default.
• W4241288183 hasRelatedWork W2318841811 @default.
• W4241288183 hasRelatedWork W2386276358 @default.
• W4241288183 hasRelatedWork W2389460111 @default.
• W4241288183 hasRelatedWork W2418671523 @default.
• W4241288183 hasVolume "86" @default.
• W4241288183 isParatext "false" @default.
• W4241288183 isRetracted "false" @default.
• W4241288183 workType "article" @default.