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- W4241341541 abstract "Sir: In the summary of their retrospective study assessing the safety and efficacy of conscious sedation for breast implant procedures, Gart et al. conclude that higher preoperative doses of diazepam in the late group significantly reduced fentanyl requirements, resulting in shorter recovery times, decreased postoperative nausea and vomiting, and elimination of unintended admissions.1 However, their results showed that the time spent in the recovery room was not significantly different between the early and late groups (149.1 minutes versus 129.1 minutes, p = 0.15). Furthermore, they did not provide and compare data on postoperative nausea and vomiting in the two groups. All four unplanned admissions (0.87 percent) due to postoperative nausea and vomiting or pain control occurred in the early group, but the authors did not specify whether risk factors for postoperative nausea and vomiting (e.g., history of postoperative nausea and vomiting or motion sickness) and postoperative analgesia scheme were comparable in the two groups. Thus, the findings of this study do not provide enough evidence to support the authors’ conclusion. This is concerning because it has been our experience that many readers do not read beyond the summary of an article, and if so, this could inadvertently mislead some readers. In addition, the crucial problem with conscious sedation is to ensure sedation without respiratory depression. In this study, the authors used three casual variables (ocular nystagmus, slurred speech, and a subjective sense of intoxication) to assess a patient’s level of preoperative sedation with diazepam. Because changes in a patient’s eyes are closely correlated with respiratory signs,2 eye signs compared with the variables used in this study are simpler and more useful to assess the adequacy of conscious sedation with hypnotic drugs. For example, during conscious sedation, patients should be able to respond to the simple phrase “open your eyes” that anesthetists say gently. Furthermore, loss of the patient’s eyelid and eyelash reflexes means an unacceptable level of deep sedation with impaired ventilatory function. Finally, as the authors have indicated, the aims of conscious sedation are to reduce or eliminate pain associated with procedures of local anesthesia and surgery, patient apprehension, and recall of intraoperative events. However, all of their postoperative follow-up data are surgery-related complications. We would like to know the incidence of their patients’ recall during conscious sedation. Because recall of intraoperative events can put patients at a risk of postoperative psychological morbidity (such as anxiety, depression, posttraumatic stress disorder, and cognitive impairment),3 it is one of the most common items for assessing safety and satisfaction of patients with conscious sedation.4 A combination of benzodiazepines and opioid drugs is commonly recommended for conscious sedation, but there are no available data regarding the impact of this sedation regimen on intraoperative recall in patients undergoing breast implant procedures. In a review of four studies with 443 cases of awake intubation, even when various combinations of sedatives and analgesics were utilized, 17 percent of patients still had partial recall and 6 percent had recall with unpleasant memories.5 Thus, without taking patients’ recall and satisfaction into account, it is arbitrary to conclude that conscious sedation is a safe and effective method of anesthesia for breast implant procedures. DISCLOSURE The authors have no financial interest to declare in relation to the content of this article. No external funding was received. Xu Liao, M.D. Fu S. Xue, M.D. Shi Y. Wang, M.D. Rui P. Li, M.D. Department of Anesthesiology Plastic Surgery Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing, People’s Republic of China" @default.
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- W4241341541 date "2013-11-01" @default.
- W4241341541 modified "2023-09-26" @default.
- W4241341541 title "Breast Implant Procedures under Conscious Sedation" @default.
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- W4241341541 doi "https://doi.org/10.1097/prs.0b013e3182a4c45e" @default.
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