Matches in SemOpenAlex for { <https://semopenalex.org/work/W4241438310> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W4241438310 abstract "<p>Recently, sunscreen-based drug photocages have been introduced to provide UV protection to photoactive drugs, thus increasing their photosafety. Here, combined experimental and theoretical studies performed on a photocage based on the commercial UVA filter avobenzone (AB) and on the photosensitizing non-steroidal anti-inflammatory drug ketoprofen (KP) are presented unveiling the photophysical processes responsible for the light-triggered release. Particular attention is paid to solvent stabilization of the drug and UV filter excited states, respectively, which leads to a switching between the triplet excited state energies of the AB and KP units. Most notably, <a>we show that the stabilization of the AB triplet excited state in ethanol solution is the key requirement for an efficient photouncaging. By contrast, in apolar solvents, in particular hexane, KP has the lowest triplet excited state, hence acting as an energy acceptor quench</a>ing the AB triplet manifold, thus inhibiting the desired photoreaction.</p>" @default.
- W4241438310 created "2022-05-12" @default.
- W4241438310 creator A5009582903 @default.
- W4241438310 creator A5024328852 @default.
- W4241438310 creator A5027517039 @default.
- W4241438310 creator A5039143845 @default.
- W4241438310 creator A5065679195 @default.
- W4241438310 creator A5083108613 @default.
- W4241438310 date "2020-12-10" @default.
- W4241438310 modified "2023-09-29" @default.
- W4241438310 title "Triplet Stabilization for the Enhanced Drug Photorelease from Sunscreen-Based Photocages" @default.
- W4241438310 doi "https://doi.org/10.26434/chemrxiv.13194110" @default.
- W4241438310 hasPublicationYear "2020" @default.
- W4241438310 type Work @default.
- W4241438310 citedByCount "0" @default.
- W4241438310 crossrefType "posted-content" @default.
- W4241438310 hasAuthorship W4241438310A5009582903 @default.
- W4241438310 hasAuthorship W4241438310A5024328852 @default.
- W4241438310 hasAuthorship W4241438310A5027517039 @default.
- W4241438310 hasAuthorship W4241438310A5039143845 @default.
- W4241438310 hasAuthorship W4241438310A5065679195 @default.
- W4241438310 hasAuthorship W4241438310A5083108613 @default.
- W4241438310 hasBestOaLocation W42414383101 @default.
- W4241438310 hasConcept C120665830 @default.
- W4241438310 hasConcept C121332964 @default.
- W4241438310 hasConcept C178790620 @default.
- W4241438310 hasConcept C181500209 @default.
- W4241438310 hasConcept C184779094 @default.
- W4241438310 hasConcept C185592680 @default.
- W4241438310 hasConcept C2779228147 @default.
- W4241438310 hasConcept C2780035454 @default.
- W4241438310 hasConcept C2780471494 @default.
- W4241438310 hasConcept C2780744026 @default.
- W4241438310 hasConcept C32909587 @default.
- W4241438310 hasConcept C43617362 @default.
- W4241438310 hasConcept C71924100 @default.
- W4241438310 hasConcept C75473681 @default.
- W4241438310 hasConcept C76766466 @default.
- W4241438310 hasConcept C98274493 @default.
- W4241438310 hasConceptScore W4241438310C120665830 @default.
- W4241438310 hasConceptScore W4241438310C121332964 @default.
- W4241438310 hasConceptScore W4241438310C178790620 @default.
- W4241438310 hasConceptScore W4241438310C181500209 @default.
- W4241438310 hasConceptScore W4241438310C184779094 @default.
- W4241438310 hasConceptScore W4241438310C185592680 @default.
- W4241438310 hasConceptScore W4241438310C2779228147 @default.
- W4241438310 hasConceptScore W4241438310C2780035454 @default.
- W4241438310 hasConceptScore W4241438310C2780471494 @default.
- W4241438310 hasConceptScore W4241438310C2780744026 @default.
- W4241438310 hasConceptScore W4241438310C32909587 @default.
- W4241438310 hasConceptScore W4241438310C43617362 @default.
- W4241438310 hasConceptScore W4241438310C71924100 @default.
- W4241438310 hasConceptScore W4241438310C75473681 @default.
- W4241438310 hasConceptScore W4241438310C76766466 @default.
- W4241438310 hasConceptScore W4241438310C98274493 @default.
- W4241438310 hasLocation W42414383101 @default.
- W4241438310 hasOpenAccess W4241438310 @default.
- W4241438310 hasPrimaryLocation W42414383101 @default.
- W4241438310 hasRelatedWork W12334191 @default.
- W4241438310 hasRelatedWork W16051966 @default.
- W4241438310 hasRelatedWork W19365561 @default.
- W4241438310 hasRelatedWork W23226003 @default.
- W4241438310 hasRelatedWork W25946987 @default.
- W4241438310 hasRelatedWork W26036575 @default.
- W4241438310 hasRelatedWork W26746109 @default.
- W4241438310 hasRelatedWork W26829069 @default.
- W4241438310 hasRelatedWork W3197963 @default.
- W4241438310 hasRelatedWork W36982308 @default.
- W4241438310 isParatext "false" @default.
- W4241438310 isRetracted "false" @default.
- W4241438310 workType "article" @default.