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- W4241501707 abstract "Atherosclerosis is a leading cause of death in the United States and worldwide; it originates from a plaque which builds up in the artery. In this paper, we consider a simplified model of plaque growth involving LDL and HDL cholesterols, macrophages and foam cells, which satisfy a coupled system of PDEs with a free boundary, the interface between the plaque and the blood flow. We prove that there exist small radially symmetric stationary plaques and establish a sharp condition that ensures their stability. We also determine necessary and sufficient conditions under which a small initial plaque will shrink and disappear, or persist for all times." @default.
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- W4241501707 date "2011-09-01" @default.
- W4241501707 modified "2023-09-27" @default.
- W4241501707 title "Modeling, simulation, and applied optimization" @default.
- W4241501707 doi "https://doi.org/10.1016/j.jfranklin.2011.06.012" @default.
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