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- W4241556834 abstract "Synopsis We reveal that the majority of EVs are released from the apical side of polarized cells and that the asymmetrical difference in EV release between the apical and basolateral sides is because of each membrane's unique distribution of phosphoinositides (PtdIns). Indeed, PtdIns(4,5)-P2 (enriched at the apical membrane) promotes the release of EVs, while PtdIns(3,4,5)-P3 (enriched at the basolateral membrane) has an inhibitory effect on EV release. Furthermore, we discovered that the v-SNARE VAMP8 regulates EV release from the basolateral membrane." @default.
- W4241556834 created "2022-05-12" @default.
- W4241556834 date "2021-04-01" @default.
- W4241556834 modified "2023-09-23" @default.
- W4241556834 doi "https://doi.org/10.1111/tra.v22.4" @default.
- W4241556834 hasPublicationYear "2021" @default.
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