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- W4241574281 abstract "Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the United States (1). We mined published microarray data (2, 3, 4) to identify differentially expressed genes in NSCLC. We found that the gene encoding the junctional adhesion molecule 2, JAM2, also known as vascular endothelial (VE)-JAM, was among those whose expression was most different in human NSCLC tumors as compared to the lung. JAM2 expression levels were significantly decreased in NSCLC tumors as compared to the lung, and lower expression of JAM2 in patient tumors was significantly associated with worse overall survival. JAM2 may be important for initiation or progression of non-small cell lung cancer in humans." @default.
- W4241574281 created "2022-05-12" @default.
- W4241574281 creator A5024900493 @default.
- W4241574281 date "2020-10-17" @default.
- W4241574281 modified "2023-09-29" @default.
- W4241574281 title "The junctional adhesion molecule 2, JAM2, is differentially expressed in non-small cell lung cancer and associates with patient survival." @default.
- W4241574281 doi "https://doi.org/10.31219/osf.io/p8tb6" @default.
- W4241574281 hasPublicationYear "2020" @default.
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