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- W4241608547 abstract "Within this chapter we summarize the multiple approaches to transcriptional profiling of peripheral blood cells, including the description and characterization of various methodologies. Additionally, we will highlight the advantages and potential pitfalls of these methodologies, especially with regard to application in multi-center clinical trials. Although gene expression profiling after instant whole blood stabilization appears to be superior to expression analysis of isolated cell populations, differences in blood leukocyte composition, high globin RNA content and genomic DNA contamination may affect the results. Thus, the choice of the peripheral blood collection and preparation method must be based on theoretical and practical concerns." @default.
- W4241608547 created "2022-05-12" @default.
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- W4241608547 date "2008-01-01" @default.
- W4241608547 modified "2023-10-01" @default.
- W4241608547 title "Whole blood" @default.
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- W4241608547 doi "https://doi.org/10.1007/978-3-7643-8334-3_2" @default.
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