Matches in SemOpenAlex for { <https://semopenalex.org/work/W4241781164> ?p ?o ?g. }
Showing items 1 to 48 of
48
with 100 items per page.
- W4241781164 endingPage "5616" @default.
- W4241781164 startingPage "5613" @default.
- W4241781164 abstract "Propargylic sulfones 1 and 2 have been synthesized for their potent interactions with DNA. The crown ether conjugate 8 was also prepared from 1 under carefully established reaction conditions. The synthesized propargylic sulfones 2, 5, and 8 exhibited high reactivity toward sulfur-, nitrogen-, and oxygen-containing nucleophiles. Compound 1 showed an IC50 of 5.3×10−6 M against KB/P cancer cells comparable with that of the clinically used agent 5-FU." @default.
- W4241781164 created "2022-05-12" @default.
- W4241781164 creator A5055383634 @default.
- W4241781164 date "1995-07-31" @default.
- W4241781164 modified "2023-10-01" @default.
- W4241781164 title "Synthesis, Reaction, and Cytotoxicity of Novel Propargylic Sulfones" @default.
- W4241781164 doi "https://doi.org/10.1016/00404-0399(50)1169i-" @default.
- W4241781164 hasPublicationYear "1995" @default.
- W4241781164 type Work @default.
- W4241781164 citedByCount "0" @default.
- W4241781164 crossrefType "journal-article" @default.
- W4241781164 hasAuthorship W4241781164A5055383634 @default.
- W4241781164 hasConcept C109316439 @default.
- W4241781164 hasConcept C178790620 @default.
- W4241781164 hasConcept C185592680 @default.
- W4241781164 hasConcept C202751555 @default.
- W4241781164 hasConcept C21951064 @default.
- W4241781164 hasConcept C2778806918 @default.
- W4241781164 hasConcept C55493867 @default.
- W4241781164 hasConcept C71240020 @default.
- W4241781164 hasConceptScore W4241781164C109316439 @default.
- W4241781164 hasConceptScore W4241781164C178790620 @default.
- W4241781164 hasConceptScore W4241781164C185592680 @default.
- W4241781164 hasConceptScore W4241781164C202751555 @default.
- W4241781164 hasConceptScore W4241781164C21951064 @default.
- W4241781164 hasConceptScore W4241781164C2778806918 @default.
- W4241781164 hasConceptScore W4241781164C55493867 @default.
- W4241781164 hasConceptScore W4241781164C71240020 @default.
- W4241781164 hasIssue "31" @default.
- W4241781164 hasLocation W42417811641 @default.
- W4241781164 hasOpenAccess W4241781164 @default.
- W4241781164 hasPrimaryLocation W42417811641 @default.
- W4241781164 hasRelatedWork W10764558 @default.
- W4241781164 hasRelatedWork W15665810 @default.
- W4241781164 hasRelatedWork W1785813 @default.
- W4241781164 hasRelatedWork W20525805 @default.
- W4241781164 hasRelatedWork W21319561 @default.
- W4241781164 hasRelatedWork W26538153 @default.
- W4241781164 hasRelatedWork W28722446 @default.
- W4241781164 hasRelatedWork W41281844 @default.
- W4241781164 hasRelatedWork W10440690 @default.
- W4241781164 hasRelatedWork W6086922 @default.
- W4241781164 hasVolume "36" @default.
- W4241781164 isParatext "false" @default.
- W4241781164 isRetracted "false" @default.
- W4241781164 workType "article" @default.