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- W4241837363 abstract "Liver flukes are multicellular parasites which belong to the trematode family. Liver fluke infection is associated with cholangiocarcinoma. Clonorchis and Opisthorchis liver flukes are parasitic flatworms; as their name implies they are flat and are lancet shaped. The life cycle is similar to that of schistosomes, but is more complex, with two intermediate hosts. Cholangiocarcinoma is the only cancer unequivocally linked to liver fluke infection. It is the second commonest primary liver cancer. Incidence and mortality for intrahepatic cholangiocarcinoma (ICC) are reported to be rising globally, while those for extrahepatic cholangiocarcinoma (ECC) are falling. The increasing incidence of ICC cannot be linked to liver fluke infestation, as the parasites cannot be transmitted outwith the known endemic areas due to the absence of their obligate intermediate host. Fluke-related cholangiocarcinoma is exclusively present in those areas in which there is both fluke endemicity and presence of the intermediate host species." @default.
- W4241837363 created "2022-05-12" @default.
- W4241837363 date "2010-10-22" @default.
- W4241837363 modified "2023-10-17" @default.
- W4241837363 title "Liver flukes" @default.
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- W4241837363 doi "https://doi.org/10.1002/9780470753651.ch13" @default.
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