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- W4241902730 abstract "<sec> <title>BACKGROUND</title> Digital health interventions (DHI) have revolutionised the management of multiple sclerosis (MS). It is now understood that the technological elements that comprise DHIs can influence participant engagement and that people with MS (PwMS) can experience significant barriers to remaining enrolled in DHIs related to the use of these elements. It is essential to explore the influence of technological elements in mitigating attrition after allocation. </sec> <sec> <title>OBJECTIVE</title> We examined the study design and technological elements of documented DHIs targeted at PwMS and how these correlated with attrition among participants of randomised-controlled trials (RCTs). </sec> <sec> <title>METHODS</title> We conducted a systematic review and meta-analysis of RCTs (n=17) describing digital technologies for health interventions for PwMS. We analysed attrition of included studies using a random-effects model and meta-regression to measure the association between potential moderators. </sec> <sec> <title>RESULTS</title> There were no measured differences in attrition between intervention and control arms; however, some of the heterogeneity observed was explained by the composite technological element score. The pooled attrition rates for the intervention and control arms were 10.6% and 11.2% respectively. </sec> <sec> <title>CONCLUSIONS</title> Ultimately, this paper provides insight into the technological composition of DHIs and will aid in the design of future studies in this area. </sec>" @default.
- W4241902730 created "2022-05-12" @default.
- W4241902730 creator A5013959040 @default.
- W4241902730 date "2021-02-04" @default.
- W4241902730 modified "2023-09-24" @default.
- W4241902730 title "Systematic review and meta-analysis of attrition within digital health interventions for people with multiple sclerosis (Preprint)" @default.
- W4241902730 doi "https://doi.org/10.2196/preprints.27735" @default.
- W4241902730 hasPublicationYear "2021" @default.
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