Matches in SemOpenAlex for { <https://semopenalex.org/work/W4241977024> ?p ?o ?g. }
- W4241977024 endingPage "187" @default.
- W4241977024 startingPage "182" @default.
- W4241977024 abstract "<h3>Abstract</h3> In many developing and regenerating systems, tissue pattern is established through gradients of informative morphogens, but we know little about how cells interpret these. Using experimental manipulation of early chick embryos including misexpression of an inducer (VG1 or ACTIVIN) and an inhibitor (BMP4), we test two alternative models for their ability to explain how the site of primitive streak formation is positioned relative to the rest of the embryo. In one model, cells read morphogen concentrations cell-autonomously. In the other, cells sense changes in morphogen status relative to their neighborhood. We find that only the latter model can account for the experimental results, including some counter-intuitive predictions. This mechanism (which we name “neighborhood watch” model) illuminates the classic “French Flag Problem” and how positional information is interpreted by a sheet of cells. <h3>Teaser</h3> How do cells know their position in the embryo, to determine where gastrulation will start?" @default.
- W4241977024 created "2022-05-12" @default.
- W4241977024 creator A5003922229 @default.
- W4241977024 date "2003-03-01" @default.
- W4241977024 modified "2023-10-01" @default.
- W4241977024 title "Bacillus anthracis" @default.
- W4241977024 cites W104427661 @default.
- W4241977024 cites W1479973247 @default.
- W4241977024 cites W1548638618 @default.
- W4241977024 cites W1585112870 @default.
- W4241977024 cites W1591183067 @default.
- W4241977024 cites W159589303 @default.
- W4241977024 cites W1634246252 @default.
- W4241977024 cites W1661941015 @default.
- W4241977024 cites W1828020944 @default.
- W4241977024 cites W1835023025 @default.
- W4241977024 cites W1835663266 @default.
- W4241977024 cites W1938604375 @default.
- W4241977024 cites W1964942318 @default.
- W4241977024 cites W1967912874 @default.
- W4241977024 cites W1968939990 @default.
- W4241977024 cites W1969366735 @default.
- W4241977024 cites W1972450614 @default.
- W4241977024 cites W1974917488 @default.
- W4241977024 cites W1984524217 @default.
- W4241977024 cites W1991942830 @default.
- W4241977024 cites W1992591179 @default.
- W4241977024 cites W1995910871 @default.
- W4241977024 cites W1997560169 @default.
- W4241977024 cites W1997775622 @default.
- W4241977024 cites W2000206128 @default.
- W4241977024 cites W2006873337 @default.
- W4241977024 cites W2014204378 @default.
- W4241977024 cites W2017560130 @default.
- W4241977024 cites W2019763194 @default.
- W4241977024 cites W2039522732 @default.
- W4241977024 cites W2076371060 @default.
- W4241977024 cites W2080141237 @default.
- W4241977024 cites W2084069113 @default.
- W4241977024 cites W2094862899 @default.
- W4241977024 cites W2116372830 @default.
- W4241977024 cites W2118488619 @default.
- W4241977024 cites W2122451783 @default.
- W4241977024 cites W2124049078 @default.
- W4241977024 cites W2133016843 @default.
- W4241977024 cites W2133457164 @default.
- W4241977024 cites W2135069977 @default.
- W4241977024 cites W2145282362 @default.
- W4241977024 cites W2145809152 @default.
- W4241977024 cites W2172212022 @default.
- W4241977024 cites W2312947926 @default.
- W4241977024 cites W2315720833 @default.
- W4241977024 cites W2462575277 @default.
- W4241977024 cites W41859830 @default.
- W4241977024 cites W4238652022 @default.
- W4241977024 cites W4242771440 @default.
- W4241977024 cites W4255260655 @default.
- W4241977024 cites W51972187 @default.
- W4241977024 cites W95484964 @default.
- W4241977024 doi "https://doi.org/10.1136/jcp.56.3.182" @default.
- W4241977024 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12610093" @default.
- W4241977024 hasPublicationYear "2003" @default.
- W4241977024 type Work @default.
- W4241977024 citedByCount "199" @default.
- W4241977024 countsByYear W42419770242012 @default.
- W4241977024 countsByYear W42419770242013 @default.
- W4241977024 countsByYear W42419770242014 @default.
- W4241977024 countsByYear W42419770242015 @default.
- W4241977024 countsByYear W42419770242016 @default.
- W4241977024 countsByYear W42419770242017 @default.
- W4241977024 countsByYear W42419770242018 @default.
- W4241977024 countsByYear W42419770242019 @default.
- W4241977024 countsByYear W42419770242020 @default.
- W4241977024 countsByYear W42419770242021 @default.
- W4241977024 countsByYear W42419770242022 @default.
- W4241977024 countsByYear W42419770242023 @default.
- W4241977024 crossrefType "journal-article" @default.
- W4241977024 hasAuthorship W4241977024A5003922229 @default.
- W4241977024 hasBestOaLocation W42419770241 @default.
- W4241977024 hasConcept C104317684 @default.
- W4241977024 hasConcept C116675565 @default.
- W4241977024 hasConcept C123894998 @default.
- W4241977024 hasConcept C137858568 @default.
- W4241977024 hasConcept C151730666 @default.
- W4241977024 hasConcept C159047783 @default.
- W4241977024 hasConcept C166957645 @default.
- W4241977024 hasConcept C167508917 @default.
- W4241977024 hasConcept C177713679 @default.
- W4241977024 hasConcept C203014093 @default.
- W4241977024 hasConcept C203133693 @default.
- W4241977024 hasConcept C205649164 @default.
- W4241977024 hasConcept C22070199 @default.
- W4241977024 hasConcept C2777289321 @default.
- W4241977024 hasConcept C2780239966 @default.
- W4241977024 hasConcept C2780801004 @default.
- W4241977024 hasConcept C33070731 @default.
- W4241977024 hasConcept C40767141 @default.
- W4241977024 hasConcept C41810244 @default.