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- W4242014414 abstract "Die konformative Flexibilität der L-Iduronsäure ist die Schlüsseleigenschaft dieser typischen Komponente von Heparin. Drei Pentasaccharide wurden nun synthetisiert, die Analoga des aktiven Bereichs von Heparin sind und in denen die einzelne L-Iduronsäure in der 1C4-, der 4C1- bzw. der 2S0-Form fixiert ist. Nur die 2S0-Variante 1 konnte die inhibierende Wirkung von Antithrombin auf den Blutkoagulationsfaktor Xa deutlich erhöhen." @default.
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- W4242014414 date "2001-05-04" @default.
- W4242014414 modified "2023-10-16" @default.
- W4242014414 title "Synthese konformativ fixierter Kohlenhydrate: Eine Skew-Bootkonformation der L-Iduronsäure in Heparin bestimmt dessen antithrombotische Aktivität" @default.
- W4242014414 doi "https://doi.org/10.1002/1521-3757(20010504)113:9<1723::aid-ange17230>3.3.co;2-e" @default.
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