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- W4242068441 abstract "Publisher SummaryThis chapter focuses on Nanoviridae family whose two member genuses are Nanovirus and Babuvirus. This family comprises plant viruses possessing very small virions which contain a multipartite (6–8), circular, single stranded DNA genome, and which are transmitted by aphids in a circulative (nonpropagative) persistent manner. Each virion contains one component of the multipartite genome and 60 subunits of a capsid protein (CP) of about 19 kDa. The virions are 17–20 nm in diameter, and are presumably of an icosahedral T = 1 symmetry structure containing 60 subunits. They are not enveloped and capsomeres producing an angular or hexagonal outline may be evident. Six or eight circular single stranded (ss)DNAs ranging in size from 923 to 1111 nucleotides (nt) are consistently found in virion preparations of different babu- and nanovirus isolates. They are encapsidated as individual positive sense strands in separate particles. In addition, up to four different satellite-like ssDNAs of about 1000–1100 nt, also referred to as alphasatellites, are found associated with the majority of the nanovirid isolates. At least 5–7 nonstructural proteins are encoded by the mRNA(s) transcribed from the nanovirid ssDNAs and all but one of the nanovirid DNAs encode only a single protein. Based on a range of geographical isolates, there is compelling evidence that 6 and 8 DNAs are essential and form the genome of a babu- and nanovirus, respectively. Since the nanovirid DNAs and some of the biochemical events determined for nanovirid replication resemble those of the geminiviruses, their replication is also thought to occur in the nucleus through transcriptionally and replicationally active dsDNA intermediates by a rolling circle type of replication mechanism." @default.
- W4242068441 created "2022-05-12" @default.
- W4242068441 date "2012-01-01" @default.
- W4242068441 modified "2023-09-26" @default.
- W4242068441 title "Nanoviridae" @default.
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- W4242068441 doi "https://doi.org/10.1016/b978-0-12-384684-6.00038-0" @default.
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