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- W4242176056 abstract "Herpes zoster has been recognized as a distinct clinical entity for hundreds of years. Its link with chickenpox was first noted in 1888 by von Bokay, who observed that susceptible children acquired varicella after contact with patients with zoster. Subsequent studies confirmed that herpes zoster and varicella share a common causal agent, the varicella zoster virus (VZV). Although the same virus causes both diseases, varicella and zoster are usually easily differentiated. Varicella is a ubiquitous, highly contagious, exanthematous disease that occurs mostly during winter and spring and predominantly affects children. Zoster is a less common, sporadic disease characterized by a painful vesicular eruption, which is usually limited to a single dermatome, and occurs predominantly in elderly and immunocompromised persons. Varicella represents primary infection with VZV. Zoster results from reactivation of the virus that remains latent after the primary infection. VZV is a member of the herpes virus family known as Herpesviridae. Other members pathogenic for humans include herpes simplex virus, cytomegalovirus, and the Epstein-Barr virus. These viruses are morphologically indistinguishable and share a number of properties, including a remarkable propensity for establishing latent infections that persist for the life of the host. There is only one VZV serotype." @default.
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- W4242176056 date "1989-01-01" @default.
- W4242176056 modified "2023-09-26" @default.
- W4242176056 title "Herpes zoster" @default.
- W4242176056 doi "https://doi.org/10.1016/0738-081x(89)90027-8" @default.
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