Matches in SemOpenAlex for { <https://semopenalex.org/work/W4242191520> ?p ?o ?g. }
- W4242191520 endingPage "156" @default.
- W4242191520 startingPage "139" @default.
- W4242191520 abstract "Macrophages are a diverse phenotype of professional phagocytic cells derived from bone-marrow precursors and parent monocytes in the peripheral blood. They are essential for the maintenance and defence of host tissues, doing so by sensing and engulfing particulate matter and, when necessary, initiating a pro-inflammatory response. Playing such a vast number of roles in both health and disease, the activation phenotype of macrophages can vary greatly and is largely dependent on the surrounding microenvironment. These phenotypes can be mimicked in experimental macrophage models derived from monocytes and in conjunction with stimulatory factors, although given the complexity of in vivo tissue spaces these model cells are inherently imperfect. Furthermore, experimental observations generated in mice are not necessarily conserved in humans, which can hamper translational research. The following chapter aims to provide an overview of how macrophages and their parent cell-type, monocytes, are classified, their development through the myeloid lineage, and finally, the general function of macrophages." @default.
- W4242191520 created "2022-05-12" @default.
- W4242191520 creator A5038590308 @default.
- W4242191520 creator A5048929131 @default.
- W4242191520 creator A5076470375 @default.
- W4242191520 date "2011-12-21" @default.
- W4242191520 modified "2023-10-13" @default.
- W4242191520 title "The Macrophage" @default.
- W4242191520 cites W1494347482 @default.
- W4242191520 cites W1505098134 @default.
- W4242191520 cites W1573082422 @default.
- W4242191520 cites W159405567 @default.
- W4242191520 cites W1668839376 @default.
- W4242191520 cites W1871020633 @default.
- W4242191520 cites W1923917571 @default.
- W4242191520 cites W1925817305 @default.
- W4242191520 cites W1928818161 @default.
- W4242191520 cites W1949313310 @default.
- W4242191520 cites W1956258286 @default.
- W4242191520 cites W1960701436 @default.
- W4242191520 cites W1962869168 @default.
- W4242191520 cites W1965859404 @default.
- W4242191520 cites W1966100182 @default.
- W4242191520 cites W1970062316 @default.
- W4242191520 cites W1972348350 @default.
- W4242191520 cites W1973099013 @default.
- W4242191520 cites W1977633435 @default.
- W4242191520 cites W1984378291 @default.
- W4242191520 cites W1984452446 @default.
- W4242191520 cites W1985502949 @default.
- W4242191520 cites W1988940275 @default.
- W4242191520 cites W1991767791 @default.
- W4242191520 cites W1992958840 @default.
- W4242191520 cites W1995856339 @default.
- W4242191520 cites W1997813957 @default.
- W4242191520 cites W2003870922 @default.
- W4242191520 cites W2010472544 @default.
- W4242191520 cites W2012136117 @default.
- W4242191520 cites W2015954946 @default.
- W4242191520 cites W2017001156 @default.
- W4242191520 cites W2026578487 @default.
- W4242191520 cites W2034469296 @default.
- W4242191520 cites W2035817205 @default.
- W4242191520 cites W2036767516 @default.
- W4242191520 cites W2038295450 @default.
- W4242191520 cites W2054472394 @default.
- W4242191520 cites W2057064377 @default.
- W4242191520 cites W2057416951 @default.
- W4242191520 cites W2060435945 @default.
- W4242191520 cites W2062995065 @default.
- W4242191520 cites W2064026146 @default.
- W4242191520 cites W2065318089 @default.
- W4242191520 cites W2065577210 @default.
- W4242191520 cites W2068290146 @default.
- W4242191520 cites W2072891489 @default.
- W4242191520 cites W2077792952 @default.
- W4242191520 cites W2081225723 @default.
- W4242191520 cites W2085464725 @default.
- W4242191520 cites W2090203203 @default.
- W4242191520 cites W2090433023 @default.
- W4242191520 cites W2090672759 @default.
- W4242191520 cites W2091360431 @default.
- W4242191520 cites W2091493364 @default.
- W4242191520 cites W2091637866 @default.
- W4242191520 cites W2093705034 @default.
- W4242191520 cites W2094003620 @default.
- W4242191520 cites W2094197667 @default.
- W4242191520 cites W2100820895 @default.
- W4242191520 cites W2104460754 @default.
- W4242191520 cites W2106274007 @default.
- W4242191520 cites W2108723188 @default.
- W4242191520 cites W2109357160 @default.
- W4242191520 cites W2118911002 @default.
- W4242191520 cites W2120280279 @default.
- W4242191520 cites W2121233690 @default.
- W4242191520 cites W2123640179 @default.
- W4242191520 cites W2126735123 @default.
- W4242191520 cites W2128627731 @default.
- W4242191520 cites W2129284543 @default.
- W4242191520 cites W2134254929 @default.
- W4242191520 cites W2135647797 @default.
- W4242191520 cites W2135703618 @default.
- W4242191520 cites W2136722399 @default.
- W4242191520 cites W2137798077 @default.
- W4242191520 cites W2143516276 @default.
- W4242191520 cites W2149200346 @default.
- W4242191520 cites W2152414109 @default.
- W4242191520 cites W2154324225 @default.
- W4242191520 cites W2156013098 @default.
- W4242191520 cites W2158380859 @default.
- W4242191520 cites W2161965432 @default.
- W4242191520 cites W2162058891 @default.
- W4242191520 cites W2168203604 @default.
- W4242191520 cites W2171480404 @default.
- W4242191520 cites W2172089049 @default.
- W4242191520 cites W2434348074 @default.
- W4242191520 doi "https://doi.org/10.1007/978-1-61779-527-5_10" @default.
- W4242191520 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22262440" @default.