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- W4242391808 abstract "Relapsing polychondritis (RP) is a rare multisystem autoimmune disease of unknown origin characterized by recurrent episodes of inflammation and progressive destruction of cartilaginous tissues. Elastic cartilage of the ears and nose, hyaline cartilage of peripheral joints, vertebral fibrocartilage and tracheobronchial cartilage, as well as proteoglycan-rich structures of the eye, heart, blood vessels or inner ear may all be affected. In most patients RP manifests in a fluctuating but progressive course which eventually results in a significant shortening of life expectancy. The relatively uncommon occurrence, the unknown etiopathogenesis, the ambiguous clinical pattern, as well as the variety in its course and response to therapy may all contribute to the difficulties the physician must overcome when managing RP. Beside describing the main features of RP and seven clinical cases of our own, in the present review we focus on recent findings in the etiopathogenesis and novel treatment options." @default.
- W4242391808 created "2022-05-12" @default.
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- W4242391808 date "2004-10-01" @default.
- W4242391808 modified "2023-09-30" @default.
- W4242391808 title "Relapsing polychondritis" @default.
- W4242391808 doi "https://doi.org/10.1016/j.berh.2004.05.012" @default.
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