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- W4242469908 abstract "Abstract Background : To determine which components should be measured and which window settings are appropriate for computerized tomography (CT) size measurements of lung adenocarcinoma and to explore interobserver agreement and accuracy according to the 8th edition of TNM staging. Methods : One hundred sixty-five surgically resected lung adenocarcinomas earlier than stage 3A were included in this study. One radiologist and two pulmonologists independently measured the total and solid sizes of components of tumors on different window settings and assessed solidity. CT measurements were compared with pathologic size measurements. Results : In categorizing solidity, 25% of the cases showed discordant results among observers. Measuring the total size of a lung adenocarcinoma predicted pathologic invasive components to a degree similar to measuring the solid component. Lung windows were more accurate (intraclass correlation [ICC] = 0.65–0.81) than mediastinal windows (ICC = 0.20–0.72) at predicting pathologic invasive components, especially in a part-solid nodule. Interobserver agreements for measurement of solid components were good with little significant difference (lung windows, ICC = 0.89; mediastinal windows, ICC = 0.91). A high level of interobserver agreement was seen between the radiologist and the pulmonologists and between residents versus a fellow on different windows. Conclusions : A considerable percentage (25%) of discrepancies was encountered in categorizing the solidity of lesions, which may decrease the accuracy of measurements. Lung window settings may be superior to mediastinal windows for measuring lung adenocarcinomas, with comparable interobserver agreement and moderate accuracy for predicting pathologic invasive components. Keywords : lung adenocarcinoma (ADC), neoplasm staging, computed x-ray tomography, observer variation" @default.
- W4242469908 created "2022-05-12" @default.
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- W4242469908 date "2020-02-07" @default.
- W4242469908 modified "2023-09-26" @default.
- W4242469908 title "Clinical T category for lung cancer staging: A pragmatic approach for real-world practice" @default.
- W4242469908 doi "https://doi.org/10.21203/rs.2.22833/v1" @default.
- W4242469908 hasPublicationYear "2020" @default.
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