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- W4242552371 abstract "BackgroundThis study seeks to explore gender-relevant factors of medical history, sociodemographics, symptom presentation, and delay on thrombolysis administration (or recorded contraindication) in a sample of men and women with confirmed myocardial infarction (MI).MethodsCross-sectional examination of self and nurse-report data collected in the coronary care unit (CCU) from 12 hospitals across south-central Ontario, Canada. A total of 482 MI patients (347 males, 135 females; 63% response rate) were recruited.Main findingsThere was no gender difference in the report of chest pain (χ2(1) = 3.78, p = .052), or in prehospital delay time (median = 96.5 minutes). Thrombolysis was administered in 158 males (68.4%) and 50 females (50.0%) without reported contraindication. Females (median = 27 minutes) had a significantly longer interval between diagnostic electrocardiogram (ECG) and administration of a thrombolytic than males (median = 22, U = 3,056). No contraindication was indicated for not administering a thrombolytic (i.e., too late, risk of bleed) in approximately 40% of females. In accordance with clinical practice guidelines, thrombolysis was more often administered in participants with a shorter time interval between symptom onset and hospital arrival. For females, thrombolysis was more often administered in younger participants (Kruskal Wallis = 5.88).ConclusionsReducing gender, age, and socioeconomic disparities in access to thrombolysis treatment is imperative. Hospital delays with female cardiac patients may be precluding thrombolysis administration." @default.
- W4242552371 created "2022-05-12" @default.
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- W4242552371 date "2003-12-01" @default.
- W4242552371 modified "2023-10-17" @default.
- W4242552371 title "Presentation, delay, and contraindication to thrombolytic treatment in females and males with myocardial infarction" @default.
- W4242552371 doi "https://doi.org/10.1016/s1049-3867(03)00074-4" @default.
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