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- W4242803275 abstract "An analysis has been made of the effect of complexing agents on the velocity of enzyme catalyzed reactions. Complexing agents are here defined as agents which combine with enzyme proteins in a manner which results in a change in the catalytic activity of the enzyme, i.e. they produce inhibitions or stimulations. From the analysis it is possible to deduce equations governing competitive, non-competitive, apparent competitive, and apparent non-competitive inhibitions. The cases of competitive and non-competitive stimulations where the complexing agent is non-essential are considered and the corresponding equations deduced. The effects of coenzymes having various affinities for the enzyme and for the enzyme combined with substrate are also analyzed. In the case of the apparent non-competitive stimulation of fumarase by phosphate, it is shown that the results obtained by previous workers are entirely in agreement with the present kinetic analysis." @default.
- W4242803275 created "2022-05-12" @default.
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- W4242803275 date "1955-01-01" @default.
- W4242803275 modified "2023-09-27" @default.
- W4242803275 title "THE STIMULATION AND INHIBITION OF ENZYME CATALYZED REACTIONS" @default.
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- W4242803275 doi "https://doi.org/10.1139/y55-121" @default.
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