Matches in SemOpenAlex for { <https://semopenalex.org/work/W4242828595> ?p ?o ?g. }
Showing items 1 to 50 of
50
with 100 items per page.
- W4242828595 endingPage "S23" @default.
- W4242828595 startingPage "S9" @default.
- W4242828595 abstract "The effect of dexmedetomidine on the potency of bupivacaine for transversus abdominis plane (TAP) block in pediatric patients has not been investigated.The primary objective of this study was to assess the effectiveness of dexmedetomidine to decrease the concentration of bupivacaine needed for analgesia for ultrasound-guided TAP block in a pediatric patient undergoing hernia repair or hydrocelectomy.This is a randomized, double-blind, up-down, dose-finding study.Operating room.Sixty American Society of Anesthesiologists I and II patients aged 1-4 years scheduled for elective unilateral herniorrhaphy or hydrocelectomy.Patients were randomly assigned to 1 of the 2 groups: group B (0.125% bupivacaine, 1 mL/kg) TAP block or group BD (0.125% bupivacaine plus 2 μg/kg dexmedetomidine, 1 mL/kg) TAP block.The response of each child was observed for 60 seconds after skin incision and evaluated as ‘unsuccessful’ when skin incision caused a change in hemodynamic parameters (heart rate and mean blood pressure) 20% more than the preincision values. If the response was determined to be unsuccessful, the concentration of bupivacaine administrated to the next patient was increased by 0.02%. If it was successful, the concentration of bupivacaine administrated to the next patient was decreased by 0.02%.The minimum local anesthetic concentration of bupivacaine was 0.0839% (0.0137) in the B group and 0.0550% (0.0169) in the BD group. The difference was statistically significant (t = 7.165, P = .0001). The total postoperative analgesic dosage of morphine was significantly higher in the B group (0.17 ± 0.04 mg/kg) than the BD group (0.11 ± 0.02 mg/kg, P = .001).The addition of 2 μg/kg of dexmedetomidine reduced the minimum local anesthetic concentration of bupivacaine used for a TAP block and improved postoperative analgesia in children undergoing surgery for inguinal hernia repair or hydrocelectomy." @default.
- W4242828595 created "2022-05-12" @default.
- W4242828595 date "2007-09-01" @default.
- W4242828595 modified "2023-09-26" @default.
- W4242828595 title "Antenatal Fetal Surveillance" @default.
- W4242828595 doi "https://doi.org/10.1016/s1701-2163(16)32616-0" @default.
- W4242828595 hasPublicationYear "2007" @default.
- W4242828595 type Work @default.
- W4242828595 citedByCount "0" @default.
- W4242828595 crossrefType "journal-article" @default.
- W4242828595 hasConcept C141071460 @default.
- W4242828595 hasConcept C168563851 @default.
- W4242828595 hasConcept C2776814716 @default.
- W4242828595 hasConcept C2777389121 @default.
- W4242828595 hasConcept C2778994108 @default.
- W4242828595 hasConcept C2780820201 @default.
- W4242828595 hasConcept C2781302539 @default.
- W4242828595 hasConcept C2781328992 @default.
- W4242828595 hasConcept C42219234 @default.
- W4242828595 hasConcept C71924100 @default.
- W4242828595 hasConceptScore W4242828595C141071460 @default.
- W4242828595 hasConceptScore W4242828595C168563851 @default.
- W4242828595 hasConceptScore W4242828595C2776814716 @default.
- W4242828595 hasConceptScore W4242828595C2777389121 @default.
- W4242828595 hasConceptScore W4242828595C2778994108 @default.
- W4242828595 hasConceptScore W4242828595C2780820201 @default.
- W4242828595 hasConceptScore W4242828595C2781302539 @default.
- W4242828595 hasConceptScore W4242828595C2781328992 @default.
- W4242828595 hasConceptScore W4242828595C42219234 @default.
- W4242828595 hasConceptScore W4242828595C71924100 @default.
- W4242828595 hasIssue "9" @default.
- W4242828595 hasLocation W42428285951 @default.
- W4242828595 hasOpenAccess W4242828595 @default.
- W4242828595 hasPrimaryLocation W42428285951 @default.
- W4242828595 hasRelatedWork W1604678961 @default.
- W4242828595 hasRelatedWork W1992361843 @default.
- W4242828595 hasRelatedWork W2002578214 @default.
- W4242828595 hasRelatedWork W202094455 @default.
- W4242828595 hasRelatedWork W2022116026 @default.
- W4242828595 hasRelatedWork W2077817520 @default.
- W4242828595 hasRelatedWork W2215590045 @default.
- W4242828595 hasRelatedWork W2775712149 @default.
- W4242828595 hasRelatedWork W3012303985 @default.
- W4242828595 hasRelatedWork W2403020248 @default.
- W4242828595 hasVolume "29" @default.
- W4242828595 isParatext "false" @default.
- W4242828595 isRetracted "false" @default.
- W4242828595 workType "article" @default.