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- W4243028334 abstract "Effects of Carteolol on norepinephrine (NE) release were studied at 2 Hz mainly in rat hypothalamic slices. Isoproterenol at 1 and 10 nM concentration-dependently facilitated NErelease. Isoproterenol (10 nM)-induced facilitation was antagonized by 1 and 10 nM dl/-carteolol, but not antagonized by 1 nM d-carteolol. dl-Carteolol alone at 1 nM to 10 μM did not inhibit NE release. In brainstem slices, 10 nM isoproterenol also facilitated NE release, and this facilitation tended to be antagonized by 1 nM dl-carteolol. Nanomolar concentrations of Carteolol stereoselectively antagonized isoproterenol-induced facilitation of NE release via presynaptic β-adrenoceptors in rat hypothalamic slices." @default.
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- W4243028334 date "1990-01-01" @default.
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- W4243028334 title "Carteolol Is a Useful Tool to Prove the Tonically Functioning Nature of Presynaptic β-Adrenoceptors on Peripheral Noradrenergic Neurons but Not on Central Catecholaminergic Neurons" @default.
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- W4243028334 doi "https://doi.org/10.1016/s0021-5198(19)40025-5" @default.
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