Matches in SemOpenAlex for { <https://semopenalex.org/work/W4243172183> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W4243172183 abstract "Background Helminthiasis is infestation of the human body with parasitic worms and it is estimated to affect 44 million pregnancies, globally, each year. Intestinal helminthiasis is associated with blood loss and decreased supply of nutrients for erythropoiesis, resulting in iron deficiency anaemia. Over 50% of the pregnant women in low‐ and middle‐income countries suffer from iron deficiency anaemia. Though iron deficiency anaemia is multifactorial, hook worm infestation is a major contributory cause in women of reproductive age in endemic areas. Antihelminthics are highly efficacious in treating hook worm but evidence of their beneficial effect and safety, when given during pregnancy, has not been established. Objectives To determine the effects of administration of antihelminthics for soil transmitted helminths during the second or third trimester of pregnancy on maternal anaemia and pregnancy outcomes. Search methods We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (September 2008). Selection criteria All prospective randomised controlled trials evaluating the effect of administration of antihelminthics during the second or third trimester of pregnancy. Data collection and analysis Two review authors independently assessed trial quality and extracted the data. Main results Three studies (1329 women) were included in this review. Analysis showed that administration of a single dose of antihelminth in the second trimester of pregnancy is not associated with any impact on maternal anaemia in the third trimester (risk ratio (RR) 0.90; 95% confidence interval (CI) 0.68 to 1.19, random effects (2 studies, n = 1075)). Subgroup analysis on the basis of co‐interventions other than antihelminthics which included iron supplementation given to both groups in the study by Larocque et al, and a subset of the study by Torlesse et al, showed that a single dose of antihelminth along with iron supplementation throughout the second and third trimester of pregnancy was not associated with any impact on maternal anaemia in the third trimester as compared to iron supplementation alone (RR 0.76; 95% CI 0.39 to 1.45, random‐effects (2 studies, n = 1017)). No impact was found for the outcomes of low birthweight (RR 0.94; 95% CI 0.61 to 1.42 (1study; n = 950)), perinatal mortality (RR 1.10; 95% CI 0.55 to 2.22 (2 studies, n = 1089)) and preterm birth (RR 0.85; 95% CI 0.38 to 1.87 (1 study, n = 984)). Impact on infant survival at six months of age could not be evaluated because no data were available. Authors' conclusions The evidence to date is insufficient to recommend use of antihelminthics for pregnant women after the first trimester of pregnancy. More well‐designed, large scale randomised controlled trials are needed to establish the benefit of antihelminthic treatment during pregnancy." @default.
- W4243172183 created "2022-05-12" @default.
- W4243172183 creator A5020054157 @default.
- W4243172183 creator A5025205064 @default.
- W4243172183 creator A5031009188 @default.
- W4243172183 date "2009-04-15" @default.
- W4243172183 modified "2023-10-18" @default.
- W4243172183 title "Effect of administration of antihelminthics for soil transmitted helminths during pregnancy" @default.
- W4243172183 cites W1526544645 @default.
- W4243172183 cites W1598602811 @default.
- W4243172183 cites W1991005603 @default.
- W4243172183 cites W2025304812 @default.
- W4243172183 cites W2036282029 @default.
- W4243172183 cites W2039128918 @default.
- W4243172183 cites W2045225511 @default.
- W4243172183 cites W2054445248 @default.
- W4243172183 cites W2059402605 @default.
- W4243172183 cites W2068464948 @default.
- W4243172183 cites W2085337239 @default.
- W4243172183 cites W2086887015 @default.
- W4243172183 cites W2088654582 @default.
- W4243172183 cites W2153989710 @default.
- W4243172183 cites W2163705903 @default.
- W4243172183 doi "https://doi.org/10.1002/14651858.cd005547.pub2" @default.
- W4243172183 hasPublicationYear "2009" @default.
- W4243172183 type Work @default.
- W4243172183 citedByCount "26" @default.
- W4243172183 countsByYear W42431721832012 @default.
- W4243172183 countsByYear W42431721832013 @default.
- W4243172183 countsByYear W42431721832014 @default.
- W4243172183 countsByYear W42431721832015 @default.
- W4243172183 countsByYear W42431721832017 @default.
- W4243172183 countsByYear W42431721832019 @default.
- W4243172183 countsByYear W42431721832020 @default.
- W4243172183 countsByYear W42431721832021 @default.
- W4243172183 countsByYear W42431721832022 @default.
- W4243172183 countsByYear W42431721832023 @default.
- W4243172183 crossrefType "reference-entry" @default.
- W4243172183 hasAuthorship W4243172183A5020054157 @default.
- W4243172183 hasAuthorship W4243172183A5025205064 @default.
- W4243172183 hasAuthorship W4243172183A5031009188 @default.
- W4243172183 hasBestOaLocation W42431721832 @default.
- W4243172183 hasConcept C126322002 @default.
- W4243172183 hasConcept C131872663 @default.
- W4243172183 hasConcept C203014093 @default.
- W4243172183 hasConcept C2777417653 @default.
- W4243172183 hasConcept C2778248108 @default.
- W4243172183 hasConcept C2779234561 @default.
- W4243172183 hasConcept C2779703513 @default.
- W4243172183 hasConcept C2779726973 @default.
- W4243172183 hasConcept C29456083 @default.
- W4243172183 hasConcept C44249647 @default.
- W4243172183 hasConcept C54355233 @default.
- W4243172183 hasConcept C71924100 @default.
- W4243172183 hasConcept C82789193 @default.
- W4243172183 hasConcept C86803240 @default.
- W4243172183 hasConceptScore W4243172183C126322002 @default.
- W4243172183 hasConceptScore W4243172183C131872663 @default.
- W4243172183 hasConceptScore W4243172183C203014093 @default.
- W4243172183 hasConceptScore W4243172183C2777417653 @default.
- W4243172183 hasConceptScore W4243172183C2778248108 @default.
- W4243172183 hasConceptScore W4243172183C2779234561 @default.
- W4243172183 hasConceptScore W4243172183C2779703513 @default.
- W4243172183 hasConceptScore W4243172183C2779726973 @default.
- W4243172183 hasConceptScore W4243172183C29456083 @default.
- W4243172183 hasConceptScore W4243172183C44249647 @default.
- W4243172183 hasConceptScore W4243172183C54355233 @default.
- W4243172183 hasConceptScore W4243172183C71924100 @default.
- W4243172183 hasConceptScore W4243172183C82789193 @default.
- W4243172183 hasConceptScore W4243172183C86803240 @default.
- W4243172183 hasLocation W42431721831 @default.
- W4243172183 hasLocation W42431721832 @default.
- W4243172183 hasOpenAccess W4243172183 @default.
- W4243172183 hasPrimaryLocation W42431721831 @default.
- W4243172183 hasRelatedWork W2037305108 @default.
- W4243172183 hasRelatedWork W2418172017 @default.
- W4243172183 hasRelatedWork W2470633880 @default.
- W4243172183 hasRelatedWork W2614365095 @default.
- W4243172183 hasRelatedWork W2979685668 @default.
- W4243172183 hasRelatedWork W3032132160 @default.
- W4243172183 hasRelatedWork W312865844 @default.
- W4243172183 hasRelatedWork W3139108370 @default.
- W4243172183 hasRelatedWork W4206748893 @default.
- W4243172183 hasRelatedWork W4242102030 @default.
- W4243172183 isParatext "false" @default.
- W4243172183 isRetracted "false" @default.
- W4243172183 workType "reference-entry" @default.