Matches in SemOpenAlex for { <https://semopenalex.org/work/W4243556192> ?p ?o ?g. }
Showing items 1 to 53 of
53
with 100 items per page.
- W4243556192 endingPage "551" @default.
- W4243556192 startingPage "541" @default.
- W4243556192 abstract "Twenty three trimethylammonium (TMA) derivatives were tested for their action on the multiple-drugresistance (R) transfer from the R-resistant Shigella flexneri 3a strain MZ 17R to the sensitive E. coli strain K-12 C25S, and also on the inverse R-transfer from the R-resistant E. coli K-12 C17R to the sensitive Shigella flexneri 3a MZS.Among the compounds tested, dodecyl-TMA, myristyl-TMA, cetyl-TMA, octadecyl-TMA, dodecylbenzyl-TMA, myristoyl-choline and benzethonium chloride inhibited the both R-transfer in a concentration of 10∼40mcg/ml, and they also showed some antibacterial activity. By a new evaluation method excluding the antibacterial activity, they were regarded to have the specific actions on the R-transfer.Although propyl-TMA, butyl-TMA, pentyl-TMA, hexyl-TMA, octyl-TMA and benzoyl choline did neither inhibited the growth of Shigella and Escherichia, nor accelerated the growth of them, put these compounds accelerated the multiple-drug-resistance transfer from MZ 17R to C25S were observed., As for the relationship between the chemical structure and the biological action in a serial compounds of alkyl-trimethylammonium halogenides, the following fact was worth notice.The compounds holding from 3 to 8 carbons in the side chain have an accelerating effect on the multiple-drug-resistance transfer and these holding from 12 to 18 carbons have an inhibitory effect." @default.
- W4243556192 created "2022-05-12" @default.
- W4243556192 creator A5041920464 @default.
- W4243556192 creator A5054721065 @default.
- W4243556192 creator A5066224010 @default.
- W4243556192 creator A5086042185 @default.
- W4243556192 date "1966-01-01" @default.
- W4243556192 modified "2023-09-25" @default.
- W4243556192 title "Studies on the Substances Affecting the Episomic Infective Transfer System (II)" @default.
- W4243556192 doi "https://doi.org/10.3412/jsb.21.541" @default.
- W4243556192 hasPublicationYear "1966" @default.
- W4243556192 type Work @default.
- W4243556192 citedByCount "0" @default.
- W4243556192 crossrefType "journal-article" @default.
- W4243556192 hasAuthorship W4243556192A5041920464 @default.
- W4243556192 hasAuthorship W4243556192A5054721065 @default.
- W4243556192 hasAuthorship W4243556192A5066224010 @default.
- W4243556192 hasAuthorship W4243556192A5086042185 @default.
- W4243556192 hasBestOaLocation W42435561921 @default.
- W4243556192 hasConcept C104317684 @default.
- W4243556192 hasConcept C13965031 @default.
- W4243556192 hasConcept C155647269 @default.
- W4243556192 hasConcept C185592680 @default.
- W4243556192 hasConcept C2781217973 @default.
- W4243556192 hasConcept C547475151 @default.
- W4243556192 hasConcept C55493867 @default.
- W4243556192 hasConceptScore W4243556192C104317684 @default.
- W4243556192 hasConceptScore W4243556192C13965031 @default.
- W4243556192 hasConceptScore W4243556192C155647269 @default.
- W4243556192 hasConceptScore W4243556192C185592680 @default.
- W4243556192 hasConceptScore W4243556192C2781217973 @default.
- W4243556192 hasConceptScore W4243556192C547475151 @default.
- W4243556192 hasConceptScore W4243556192C55493867 @default.
- W4243556192 hasIssue "9" @default.
- W4243556192 hasLocation W42435561921 @default.
- W4243556192 hasOpenAccess W4243556192 @default.
- W4243556192 hasPrimaryLocation W42435561921 @default.
- W4243556192 hasRelatedWork W1916651533 @default.
- W4243556192 hasRelatedWork W2329438784 @default.
- W4243556192 hasRelatedWork W2415917856 @default.
- W4243556192 hasRelatedWork W2605421943 @default.
- W4243556192 hasRelatedWork W2606340465 @default.
- W4243556192 hasRelatedWork W2606739995 @default.
- W4243556192 hasRelatedWork W2606776574 @default.
- W4243556192 hasRelatedWork W2606792798 @default.
- W4243556192 hasRelatedWork W2907625880 @default.
- W4243556192 hasRelatedWork W2478742927 @default.
- W4243556192 hasVolume "21" @default.
- W4243556192 isParatext "false" @default.
- W4243556192 isRetracted "false" @default.
- W4243556192 workType "article" @default.