FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4243808052> ?p ?o ?g. }

• W4243808052 abstract "<sec> <title>BACKGROUND</title> Infectious bronchiolitis caused by respiratory capillary syncytial bronchial virus. This disease is an infectious disease of the lower respiratory tract caused by obstruction of respiratory capillary syncytial bronchial virus infection, causing respiratory obstruction and shortness of breath, difficulty breathing, and hypoxia. There are currently no reliable indicators to assess the prognosis of respiratory syncytial virus bronchiolitis and the risk of secondary bronchial asthma. In order to explore the correlation between respiratory syncytial virus bronchiolitis and bronchial asthma, experiments and mathematical statistics were used. The controlled experiment used in this paper shows that the incidence of bronchiolitis is about 20% -30% in the first year after birth and about 10% -20% in the second year. 30% -50%, this article also compared three kinds of respiratory viruses, respiratory syncytial virus infection rate is the highest, 61.4%. The results of this study show that respiratory syncytial virus infection is the main pathogen that induces asthma, especially bronchiolitis, so it is very important for patients to diagnose early and correctly understand the causes of asthma. </sec> <sec> <title>OBJECTIVE</title> In order to explore the correlation between respiratory syncytial virus bronchiolitis and bronchial asthma, experiments and mathematical statistics were used </sec> <sec> <title>METHODS</title> Respiratory Syncytial Virus Capillary Bronchitis </sec> <sec> <title>RESULTS</title> the comparison results are similar. Then, the RSV-positive bronchiolitis specimens (96 cases) were amplified and sequenced for the entire G protein gene sequence, and 40 cases of the complete G protein sequence (35 cases of subtype A and 5 cases of subtype B) were successfully obtained. The analysis results showed that 6 A subtype genotypes (NAl, NA2, NA3, NA4, GA5, ON1) and 5 B subtype genotypes (BA3, BA7, BA9, BA10, CB1) were detected. The percentage of RNA types in the exosomes of simulated and RSV infected A549 cells is shown in Table 2. Among subtype A, NA1 genotype (55.1%) and ON1 genotype (39.1%) were the dominant genotypes, and subtype B had BA9 (90.6%) as the absolute dominant genotype. </sec> <sec> <title>CONCLUSIONS</title> At present, there is a certain understanding of the relationship between respiratory syncytial virus bronchiolitis and bronchial asthma, and severe bronchiolitis and pneumonia can occur after infants with respiratory syncytial virus infection. It has a certain relationship with childhood asthma. The symptoms of the two patients ranged from severe to severe. In severe cases, breathing difficulties developed rapidly, and even life-threatening. Some respiratory syncytial virus bronchiolitis may be secondary to bronchial asthma, causing social and family economic burden. Studying the pathogenesis of respiratory syncytial virus (RSV) infection is helpful for understanding the disease. In particular, the relationship between early wheezing, the occurrence, development and prognosis of asthma has been a key direction for assisting patients in practical application. In order to explore the correlation between respiratory syncytial virus bronchiolitis and bronchial asthma, experimental methods were used to conduct controlled trials and data statistics on patients, objectively reflecting the relationship between respiratory syncytial virus bronchiolitis and bronchial asthma. This article uses a control experiment and other methods. The experiment shows that the incidence of bronchiolitis is about 20% -30% in the first year after birth and about 10% -20% in the second year. The incidence of acute wheezing disease in preschool children The incidence rate can be as high as 30% -50%, the virus positive rate is 51%, and the positive rate of M. pneumoniae is about 32%. The positive rate of bacteria detected was 25%. The virus detection rate is higher than that of Mycoplasma pneumoniae and bacteria. After statistical processing, the difference is significant. In addition, through mathematical statistics and logical analysis, it was found that IFN-γ / IL-4 and IL-10 / IL-17 in children with respiratory syncytial virus bronchiolitis and asthma were significantly reduced, while TGF- β / IL-17 was significantly lower than that of children with non-RSV pneumonia and healthy control children (P <0.05). It indicates that after RSV infection, Th2 cells and its specific cytokine IL-4 expression may be up-regulated in the body for a long time, thereby promoting the occurrence of subsequent asthma. It suggests that RSV bronchiolitis and the severity of the disease are closely related to the occurrence of asthma in the later period. The results of this study show that respiratory syncytial virus infection is the main pathogen that induces asthma, especially bronchiolitis, so it is very important for patients to diagnose early and correctly understand the causes of asthma. </sec>" @default.
• W4243808052 created "2022-05-12" @default.
• W4243808052 creator A5011487190 @default.
• W4243808052 creator A5029940259 @default.
• W4243808052 creator A5082857859 @default.
• W4243808052 date "2020-07-08" @default.
• W4243808052 modified "2023-09-29" @default.
• W4243808052 title "Respiratory Syncytial Virus Bronchiolitis and Bronchial Asthma (Preprint)" @default.
• W4243808052 cites W2280184943 @default.
• W4243808052 cites W2314455166 @default.
• W4243808052 cites W2346601085 @default.
• W4243808052 cites W2520838246 @default.
• W4243808052 cites W2531356796 @default.
• W4243808052 cites W2549958419 @default.
• W4243808052 cites W2603390079 @default.
• W4243808052 cites W2782377590 @default.
• W4243808052 cites W2782672447 @default.
• W4243808052 cites W2790505969 @default.
• W4243808052 cites W2792289345 @default.
• W4243808052 cites W2800422958 @default.
• W4243808052 cites W2802635439 @default.
• W4243808052 cites W2896802097 @default.
• W4243808052 cites W2948795783 @default.
• W4243808052 cites W2964893899 @default.
• W4243808052 cites W2980900996 @default.
• W4243808052 doi "https://doi.org/10.2196/preprints.22309" @default.
• W4243808052 hasPublicationYear "2020" @default.
• W4243808052 type Work @default.
• W4243808052 citedByCount "0" @default.
• W4243808052 crossrefType "posted-content" @default.
• W4243808052 hasAuthorship W4243808052A5011487190 @default.
• W4243808052 hasAuthorship W4243808052A5029940259 @default.
• W4243808052 hasAuthorship W4243808052A5082857859 @default.
• W4243808052 hasConcept C126322002 @default.
• W4243808052 hasConcept C159047783 @default.
• W4243808052 hasConcept C203014093 @default.
• W4243808052 hasConcept C2522874641 @default.
• W4243808052 hasConcept C2776042228 @default.
• W4243808052 hasConcept C2776178081 @default.
• W4243808052 hasConcept C2777714996 @default.
• W4243808052 hasConcept C2778821649 @default.
• W4243808052 hasConcept C2779644171 @default.
• W4243808052 hasConcept C2779993553 @default.
• W4243808052 hasConcept C2780727368 @default.
• W4243808052 hasConcept C2780813555 @default.
• W4243808052 hasConcept C2909511158 @default.
• W4243808052 hasConcept C534529494 @default.
• W4243808052 hasConcept C71924100 @default.
• W4243808052 hasConceptScore W4243808052C126322002 @default.
• W4243808052 hasConceptScore W4243808052C159047783 @default.
• W4243808052 hasConceptScore W4243808052C203014093 @default.
• W4243808052 hasConceptScore W4243808052C2522874641 @default.
• W4243808052 hasConceptScore W4243808052C2776042228 @default.
• W4243808052 hasConceptScore W4243808052C2776178081 @default.
• W4243808052 hasConceptScore W4243808052C2777714996 @default.
• W4243808052 hasConceptScore W4243808052C2778821649 @default.
• W4243808052 hasConceptScore W4243808052C2779644171 @default.
• W4243808052 hasConceptScore W4243808052C2779993553 @default.
• W4243808052 hasConceptScore W4243808052C2780727368 @default.
• W4243808052 hasConceptScore W4243808052C2780813555 @default.
• W4243808052 hasConceptScore W4243808052C2909511158 @default.
• W4243808052 hasConceptScore W4243808052C534529494 @default.
• W4243808052 hasConceptScore W4243808052C71924100 @default.
• W4243808052 hasLocation W42438080521 @default.
• W4243808052 hasOpenAccess W4243808052 @default.
• W4243808052 hasPrimaryLocation W42438080521 @default.
• W4243808052 hasRelatedWork W1128463 @default.
• W4243808052 hasRelatedWork W11591070 @default.
• W4243808052 hasRelatedWork W12519548 @default.
• W4243808052 hasRelatedWork W15112479 @default.
• W4243808052 hasRelatedWork W18893762 @default.
• W4243808052 hasRelatedWork W2229246 @default.
• W4243808052 hasRelatedWork W5138191 @default.
• W4243808052 hasRelatedWork W5251251 @default.
• W4243808052 hasRelatedWork W8585530 @default.
• W4243808052 hasRelatedWork W7888971 @default.
• W4243808052 isParatext "false" @default.
• W4243808052 isRetracted "false" @default.
• W4243808052 workType "article" @default.