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- W4243849966 abstract "Neuroendocrine tumors are ubiquitous neoplasms that may occur anywhere in the human body. Although these tumors have been recognized for more than 100 years, a unifying concept regarding classification has been controversial, and concepts introduced a century ago are still kept in use in today’s nomenclature. In addition, some of the current entities encompassed in the rubric of neuroendocrine carcinomas still require better definition and proper study. Interestingly, even though it is known that the great majority of neuroendocrine neoplasms occur in the gastrointestinal tract, most of the current concepts regarding classification and nomenclature are being driven by studies in thoracic tumors. Nevertheless, one of the issues that has been put forward to keep separate nomenclatures for these tumors in different organ systems is the supposed different clinical behavior of these neoplasms in the different systems. The emphasis in this chapter will be the morphological approach with the idea of unifying histological criteria for the diagnosis of the spectrum of these tumors whether they are in the genitourinary, gynecological, thoracic, or gastrointestinal system. The use of ancillary methods such as immunohistochemistry or electron microscopy although important will be included as a manner to refine the diagnosis." @default.
- W4243849966 created "2022-05-12" @default.
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- W4243849966 date "2011-01-01" @default.
- W4243849966 modified "2023-10-18" @default.
- W4243849966 title "Pathology" @default.
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- W4243849966 doi "https://doi.org/10.1007/978-1-60327-997-0_2" @default.
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