Matches in SemOpenAlex for { <https://semopenalex.org/work/W4243937625> ?p ?o ?g. }
Showing items 1 to 55 of
55
with 100 items per page.
- W4243937625 abstract "Large-scale proteomics is typically achieved using a bottom-up approach whereby cell extracts are proteolytically digested into peptides prior to their analysis by liquid chromatography—tandem mass spectrometry (LC—MS/MS). While this strategy is largely preferred for comprehensive protein identification, the corresponding conversion of proteins to peptides significantly increases sample complexity, and typically results in tens of thousands of peptides placing considerable demands on MS instruments to obtain in-depth proteome coverage. Current MS instrumentation enables the detection of more than 100 000 peptides in a single run, although the large majority remains inaccessible to data-dependent LC—MS/MS. In this perspective Special Feature, Pierre Thibault and co-workers describe the use of high-field asymmetric waveform ion mobility spectrometry (FAIMS) and evaluate its analytical merits for proteomic applications. Pierre Thibault is Professor of Chemistry at the Université de Montréal (Montreal QC, Canada). His main research interests are in the development and implementation of new technologies in proteomics and cell biology. In multidisciplinary research, these tools provide a deeper understanding of molecular mechanisms and posttranslational modifications, which regulate the function and translocation of proteins involved in immunity and signalling in cancer cells." @default.
- W4243937625 created "2022-05-12" @default.
- W4243937625 date "2015-11-01" @default.
- W4243937625 modified "2023-10-14" @default.
- W4243937625 doi "https://doi.org/10.1002/jms.v50.11" @default.
- W4243937625 hasPublicationYear "2015" @default.
- W4243937625 type Work @default.
- W4243937625 citedByCount "0" @default.
- W4243937625 crossrefType "journal-issue" @default.
- W4243937625 hasConcept C104317684 @default.
- W4243937625 hasConcept C104397665 @default.
- W4243937625 hasConcept C14036430 @default.
- W4243937625 hasConcept C162356407 @default.
- W4243937625 hasConcept C171250308 @default.
- W4243937625 hasConcept C185592680 @default.
- W4243937625 hasConcept C192562407 @default.
- W4243937625 hasConcept C31827203 @default.
- W4243937625 hasConcept C43617362 @default.
- W4243937625 hasConcept C46111723 @default.
- W4243937625 hasConcept C55493867 @default.
- W4243937625 hasConcept C70721500 @default.
- W4243937625 hasConcept C86803240 @default.
- W4243937625 hasConcept C95444343 @default.
- W4243937625 hasConceptScore W4243937625C104317684 @default.
- W4243937625 hasConceptScore W4243937625C104397665 @default.
- W4243937625 hasConceptScore W4243937625C14036430 @default.
- W4243937625 hasConceptScore W4243937625C162356407 @default.
- W4243937625 hasConceptScore W4243937625C171250308 @default.
- W4243937625 hasConceptScore W4243937625C185592680 @default.
- W4243937625 hasConceptScore W4243937625C192562407 @default.
- W4243937625 hasConceptScore W4243937625C31827203 @default.
- W4243937625 hasConceptScore W4243937625C43617362 @default.
- W4243937625 hasConceptScore W4243937625C46111723 @default.
- W4243937625 hasConceptScore W4243937625C55493867 @default.
- W4243937625 hasConceptScore W4243937625C70721500 @default.
- W4243937625 hasConceptScore W4243937625C86803240 @default.
- W4243937625 hasConceptScore W4243937625C95444343 @default.
- W4243937625 hasIssue "11" @default.
- W4243937625 hasLocation W42439376251 @default.
- W4243937625 hasOpenAccess W4243937625 @default.
- W4243937625 hasPrimaryLocation W42439376251 @default.
- W4243937625 hasRelatedWork W2050333409 @default.
- W4243937625 hasRelatedWork W2080856312 @default.
- W4243937625 hasRelatedWork W2086860678 @default.
- W4243937625 hasRelatedWork W2109364024 @default.
- W4243937625 hasRelatedWork W2114332462 @default.
- W4243937625 hasRelatedWork W2337002289 @default.
- W4243937625 hasRelatedWork W3187594710 @default.
- W4243937625 hasRelatedWork W4245370043 @default.
- W4243937625 hasRelatedWork W4289550775 @default.
- W4243937625 hasRelatedWork W4323833131 @default.
- W4243937625 hasVolume "50" @default.
- W4243937625 isParatext "false" @default.
- W4243937625 isRetracted "false" @default.
- W4243937625 workType "paratext" @default.