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- W4244045401 endingPage "116" @default.
- W4244045401 startingPage "100" @default.
- W4244045401 abstract "Mechanical loading as a result of load-bearing physical activity is an important regulator of both bone mass and bone microarchitecture. Sex hormone receptor signaling involves several separate signaling cascades in a tissue-specific manner, affecting osteoclastic resorption, osteoblastic bone formation, bone modeling and remodeling, and is also an important determinant of bone mass. Interestingly, estrogen receptors play an important role in load-induced modeling of bone, an effect surprisingly found to be independent of estrogen. Modeling of jaw bones in response to orthodontic tooth movement is dependent on several factors where reshaping of bone by osteoclast and osteoblast activities are of major importance. Although not much studied, loading, sex hormones, and their receptors are likely to affect orthodontic tooth movement. This chapter gives an overview of bone cell differentiation and function and describes the role of sex hormone receptors in mechanical loading, and their possible role in orthodontic tooth movement." @default.
- W4244045401 created "2022-05-12" @default.
- W4244045401 creator A5013708191 @default.
- W4244045401 creator A5047793230 @default.
- W4244045401 date "2021-03-10" @default.
- W4244045401 modified "2023-09-27" @default.
- W4244045401 title "Mechanical Load, Sex Hormones, and Bone Modeling" @default.
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