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- W4244094911 abstract "We report on the state of the art of scientific literature about proteins recognized as potential targets for the development of Leishmania treatments through the search of biologically active chemical species, either from experimental in vitro, in vivo, or in silico sources. We classify the gathered information, in several ways: vector taxonomy and geographical distribution, parasite taxonomic and geographical distribution and enzymatic function (oxidoreductases, transferases, hydrolases, lyases, isomerases, ligases and cytokines). Our aim is to provide a much needed reference layout for research efforts aimed to understand the underpinning physical interactions in ligand-protein activation/inactivation processes. In the specific case of Leishmania, we focus on enzymes known to be part of the biochemical molecular processes initiated following a Leishmania infectious episode." @default.
- W4244094911 created "2022-05-12" @default.
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- W4244094911 date "2020-02-21" @default.
- W4244094911 modified "2023-09-27" @default.
- W4244094911 title "<em>Leishmania</em> Proteomics: An <em>in Silico</em> Perspective" @default.
- W4244094911 doi "https://doi.org/10.20944/preprints201902.0122.v3" @default.
- W4244094911 hasPublicationYear "2020" @default.
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