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- W4244127029 abstract "Bupropion (BUP), a dopamine/norepinephrine re-uptake inhibitor and an activator of proopiomelanocortin signaling, has been used clinically to treat depression, smoking addiction, and eating disorder. Here we show that BUP, alone and in combination with naltrexone, reduces binge-like ethanol consumption in male mice. These data suggest that BUP may represent a novel approach to treating binge ethanol intake, which we are currently assessing in a Phase II clinical trial experiment." @default.
- W4244127029 created "2022-05-12" @default.
- W4244127029 date "2019-05-01" @default.
- W4244127029 modified "2023-09-26" @default.
- W4244127029 doi "https://doi.org/10.1111/acer.2019.43.issue-5" @default.
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