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- W4244201757 abstract "In tertiary MEF undergoing cell cycle progression, autocrine interferon (IFN) is released and constitutive levels of 2′,5′-oligoadenylate (2-5A) synthetase activity, low through the cell cycle, surge into a peak within S phase. Treatment of MEF with the autocrine IFN they produce elicits a 2-5A synthetase response from cells positioned in G0 but not from cells in G1 and from cells in S phase. Neutralization of the autocrine IFN by antibody shortens the length of G1 leaving unaltered the kinetics of progression through S and G2 and has no effect on the S phase-linked expression of 2-5A synthetase activity. The growth controlling effect of the autocrine IFN has been mapped to the second part of G1." @default.
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- W4244201757 date "1992-05-01" @default.
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- W4244201757 title "Cell Cycle Regulation (G1) by Autocrine Interferon and Dissociation between Autocrine Interferon and 2′,5′-01igoadenylate Synthetase Expression" @default.
- W4244201757 doi "https://doi.org/10.1089/jir.1992.1992.51" @default.
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