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- W4244278045 abstract "Multiple applications of isothioureas as fine chemicals (or their precursors) are known, but a general sustainable method for their synthesis was hitherto unavailable. We report a novel general approach towards S-alkyl and S-aryl isothioureas through a copper(I)-catalyzed three-component reaction between amines, isocyanides, and thiosulfonates. The formal synthesis of a superpotent sweetener further illustrates the applicability of our method." @default.
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- W4244278045 date "2014-09-15" @default.
- W4244278045 modified "2023-10-01" @default.
- W4244278045 title "Sustainable Three-Component Synthesis of Isothioureas from Isocyanides, Thiosulfonates, and Amines" @default.
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- W4244278045 doi "https://doi.org/10.1002/ange.201406717" @default.
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