Matches in SemOpenAlex for { <https://semopenalex.org/work/W4244339946> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W4244339946 abstract "In the CNS, minor changes in the concentration of neurotransmitters such as glutamate or dopamine can lead to neurodegenerative diseases. We present an evolutionary perspective on the function of neurotransmitter toxicity in the CNS. We hypothesize that neurotransmitters are selected because of their toxicity, which serves as a test of neuron quality and facilitates the selection of neuronal pathways. This perspective may offer additional explanations for the reduction of neurotransmitter concentration in the CNS with age, and suggest an additional role for the blood-brain barrier. It may also suggest a connection between the specific toxicity of the neurotransmitters released in a specific region of the CNS, and elucidate their role as chemicals that are optimal for testing the quality of cells in that region." @default.
- W4244339946 created "2022-05-12" @default.
- W4244339946 creator A5026464707 @default.
- W4244339946 creator A5076318490 @default.
- W4244339946 creator A5082297655 @default.
- W4244339946 date "2014-07-30" @default.
- W4244339946 modified "2023-09-29" @default.
- W4244339946 title "Why are neurotransmitters neurotoxic? An evolutionary perspective" @default.
- W4244339946 doi "https://doi.org/10.12688/f1000research.4828.1" @default.
- W4244339946 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25580225" @default.
- W4244339946 hasPublicationYear "2014" @default.
- W4244339946 type Work @default.
- W4244339946 citedByCount "3" @default.
- W4244339946 countsByYear W42443399462015 @default.
- W4244339946 countsByYear W42443399462019 @default.
- W4244339946 countsByYear W42443399462021 @default.
- W4244339946 crossrefType "journal-article" @default.
- W4244339946 hasAuthorship W4244339946A5026464707 @default.
- W4244339946 hasAuthorship W4244339946A5076318490 @default.
- W4244339946 hasAuthorship W4244339946A5082297655 @default.
- W4244339946 hasBestOaLocation W42443399461 @default.
- W4244339946 hasConcept C126322002 @default.
- W4244339946 hasConcept C169760540 @default.
- W4244339946 hasConcept C170493617 @default.
- W4244339946 hasConcept C2776219046 @default.
- W4244339946 hasConcept C2778794669 @default.
- W4244339946 hasConcept C2910715078 @default.
- W4244339946 hasConcept C29730261 @default.
- W4244339946 hasConcept C513476851 @default.
- W4244339946 hasConcept C529278444 @default.
- W4244339946 hasConcept C55493867 @default.
- W4244339946 hasConcept C61174792 @default.
- W4244339946 hasConcept C71924100 @default.
- W4244339946 hasConcept C86803240 @default.
- W4244339946 hasConcept C98274493 @default.
- W4244339946 hasConceptScore W4244339946C126322002 @default.
- W4244339946 hasConceptScore W4244339946C169760540 @default.
- W4244339946 hasConceptScore W4244339946C170493617 @default.
- W4244339946 hasConceptScore W4244339946C2776219046 @default.
- W4244339946 hasConceptScore W4244339946C2778794669 @default.
- W4244339946 hasConceptScore W4244339946C2910715078 @default.
- W4244339946 hasConceptScore W4244339946C29730261 @default.
- W4244339946 hasConceptScore W4244339946C513476851 @default.
- W4244339946 hasConceptScore W4244339946C529278444 @default.
- W4244339946 hasConceptScore W4244339946C55493867 @default.
- W4244339946 hasConceptScore W4244339946C61174792 @default.
- W4244339946 hasConceptScore W4244339946C71924100 @default.
- W4244339946 hasConceptScore W4244339946C86803240 @default.
- W4244339946 hasConceptScore W4244339946C98274493 @default.
- W4244339946 hasLocation W42443399461 @default.
- W4244339946 hasLocation W42443399462 @default.
- W4244339946 hasLocation W42443399463 @default.
- W4244339946 hasOpenAccess W4244339946 @default.
- W4244339946 hasPrimaryLocation W42443399461 @default.
- W4244339946 hasRelatedWork W122150940 @default.
- W4244339946 hasRelatedWork W1262889361 @default.
- W4244339946 hasRelatedWork W2020393851 @default.
- W4244339946 hasRelatedWork W2024747286 @default.
- W4244339946 hasRelatedWork W2041103604 @default.
- W4244339946 hasRelatedWork W2056676407 @default.
- W4244339946 hasRelatedWork W2058636883 @default.
- W4244339946 hasRelatedWork W2464212103 @default.
- W4244339946 hasRelatedWork W2953322381 @default.
- W4244339946 hasRelatedWork W87155003 @default.
- W4244339946 isParatext "false" @default.
- W4244339946 isRetracted "false" @default.
- W4244339946 workType "article" @default.